摘要
目的分析腹腔镜全结直肠切除回肠储袋肛管吻合术(IPAA)对溃疡性结肠炎(UC)患者术后肠道功能与生活质量的影响。方法回顾性分析2014-2017年浙江大学医学院附属邵逸夫医院行IPAA手术的37例UC患者的临床资料,采用炎症性肠病生活质量问卷(IBDQ)和肠道功能问卷调查患者的生活质量及肠道功能,分析IPAA术对患者术后的影响。结果本组37例患者均行腹腔镜IPAA术,其中25例为2期IPAA术式,12例为3期IPAA术式。2期手术患者术后排便习惯优于3期手术患者(t=6.72,P<0.05);年龄>45岁组每日排便次数多于年龄≤45岁组(1=3.49,P<0.05),并且年龄较大患者晚上漏便率高于年龄较低患者(<45岁)(t=5.28,P<0.05)。并发储袋炎患者的IBDQ肠道症状总分低于无储袋炎患者(r=0.330,P<0.05);年龄>45岁组在全身症状(r=0.349,P<0.05)和情绪功能(r=0.379,P<0.05)方面总分高于手术年龄≤45岁组。结论UC患者行IPAA术的疗效较好,术后肠道功能和生活质量与年龄有一定关系,手术分期影响术后排便习惯。
Objectives To assess bowel function and quality of life in patients with ulcerative colitis(UC)after ileal pouch anal anastomosis(IPAA).Methods Clinical data of 37 UC patients after IPAA between 2014 and 2017 were retrospectively analyzed at Sir Run Run Shaw Hospital School of Medieine Zhejiang University.The IBDQ and Bowel Function questionnaire were used for analyzing correlation between elinical variables and quality of life or bowel function.Results Laparoscopic operation was performed in 12 eases at stage 2 and 25 cases at stage 3.Postoperative defecation of stage 3 patients were better than that of stage2(t=6.72,P<0.05).The mumber of daily defecation in age>45-year-old group was more than that in<45-year-old(t=3.49,P<0.05),and the rate of evening stol seepage in the older group was higher than in the younger group(t=5.28,P<0.05).The total score of intestinal symptoms of IBDQ in patients of pouchitis was lower than that without pouchitis(r=0.330,P<0.05).The total score in age>45 in terms of systemie symptoms(r=0.349,P<0.05)and emotional function(r=0.379,P<0.05)was higher than age<45.Conclusions Outcomes of UC patients after IPAA are satisfactory,bowel function and quality of life is related with age,and stage of IPAA afet postoperative defecation.
作者
徐海利
葛晓龙
刘威
戚卫林
叶玲娜
曹倩
潘红英
周伟
Xu Haili;Ge Xiaolong;Liu Wei;Qi Weilin;Ye Linna;Cao Qian;Pan Hongying;Zhou Wei(Department of General Surgery,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University,Hangzhou 310016,China;Department of Gastroenterology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University,Hangzhou 310016,China)
出处
《中华普通外科杂志》
CSCD
北大核心
2021年第2期122-126,共5页
Chinese Journal of General Surgery
作者简介
通信作者:潘红英,Email:3191016@zju.edu.cn,电话:0571-86006396。
