摘要
结直肠腺瘤性息肉(colorectal adenomatous polyps,CAP)是结直肠癌(colorectal cancer,CRC)的癌前病变,随着饮食习惯、生活方式的改变,CAP的发病率逐年上升。大多数CAP一般以“腺瘤-腺癌”发展,发现并控制CAP的危险因素和保护因素是降低CRC发病率的关键。CAP的发生与遗传、年龄、饮食习惯、肠道环境等多种因素相互作用有关,因此,深入研究CAP的危险因素,对降低CAP的发生具有重要意义。本文对CAP的相关因素和机制的研究进展进行一综述,以期通过控制CAP的相关因素降低CRC的发病率。
Colorectal adenomatous polyps(CAPs)are recognized precancerous lesion of colorectal cancer(CRC).With the change of the diet and lifestyle,the incidence of CAP rise in recent years.Most of CAP will develop following a adenoma-cancer process.To find and control the risk factors and protective factors of CAP are the key to reduce the incidence of CRC.Research have shown that the occurrence of CAP is related to many factors such as genetic,age,diet and the intestinal environment interaction.Therefore,it is great significant for reducing the occurrence of CAP to research the risk factors of CAP deeply.In this paper,we summarize some advances of the research in the related factors and mechanism of CAP,in order to reduce the incidence of CRC.
作者
陆瑶
赵公芳
徐泉
张曦予
Lu Yao;Zhao Gongfang;Xu Quan;Zhang Xiyu(Digestive Medicine Department,the Second Affiliated Hospital of Kunming Medical College,Kunming 650000,Yunnan,China)
出处
《消化肿瘤杂志（电子版）》
2020年第4期233-237,共5页
Journal of Digestive Oncology(Electronic Version)
关键词
结直肠腺瘤性息肉
相关因素
相关机制
综述
Colorectal adenomatous polyps
Related factors
Related mechanism
Review
作者简介
第一作者:陆瑶,硕士研究生;通信作者:赵公芳,副主任医师,E-mail:zhaogongfang@163.com。
