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腹腔镜下宫颈癌根治术治疗早期子宫颈癌临床研究 被引量:20

Clinical effect of laparoscopic radical hysterectomy in treatment of early cervical cancer
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摘要 目的:探讨早期子宫颈癌患者应用腹腔镜下宫颈癌根治术治疗的临床疗效。方法:80例早期子宫颈癌患者,采用随机数字表法分为对照组(传统开腹手术治疗)和观察组(腹腔镜下宫颈癌根治术治疗),每组患者40例。对比住院时间、尿管留置时间、术后排气时间、切除淋巴结数目、术中出血量、手术时间、术后并发症发生情况,并于治疗1年后对患者进行随访,了解其复发、转移、死亡情况。结果:经治疗后,对照组患者的切除淋巴结数目(18.76±1.22)个、手术时间(191.21±10.87)min与观察组患者的切除淋巴结数目(19.32±1.25)个、手术时间(194.32±10.90)min,两组比较差异均无统计学意义(均P>0.05);观察组患者住院时间(13.28±1.98)d、尿管留置时间(15.99±1.99)h、术后排气时间(35.87±3.65)h以及术中出血量(192.32±9.65)ml显著低于对照组患者的住院时间(21.76±3.23)d、尿管留置时间(35.88±4.22)h、术后排气时间(54.01±6.98)h以及术中出血量(429.80±17.98)ml,两组比较差异均有统计学意义(均P<0.05);观察组术后并发症发生率(7.50%)显著低于对照组术后并发症发生率(35.00%),两组比较差异有统计学意义(P<0.05);两组随访期间无复发、死亡患者,但对照组有1例患者出现淋巴结转移,转移率为2.50%,两组相比差异无统计学意义(P>0.05)。结论:对于早期子宫颈癌患者,应用腹腔镜下宫颈癌根治术治疗可显著提高切除淋巴结数目,减少术中出血量、缩短术后尿管留置时间、术后排气时间,术后并发症发生率低,有较高临床应用价值。 Objective:To analyze the clinical effect of laparoscopic radical hysterectomy in the treatment of early cervical cancer.Methods:80 patients with early cervical cancer were selected and randomly divided into control group(traditional laparotomy)and observation group(laparoscopic radical operation),40 cases in each group.The hospitalization time,indwelling time of urinary catheter,exhaust time after operation,number of lymph nodes resected,intraoperative blood loss,operation time and complications were compared.The patients were followed up one year after treatment to understand the recurrence,metastasis and death.Results:After treatment,the number of lymph nodes resected(18.76±1.22)and operation time[(191.21±10.87)min]in the control group were compared with the number of lymph nodes resected(19.32±1.25)and operation time[(194.32±10.90)min]in the observation group,and there was no statistical difference(all P>0.05).In the observation group,the hospitalization time was(13.28±1.98)days,the indwelling time of urinary catheter was(15.99±1.99)hours,the time of exhaust after operation was(35.87±3.65)hours,and the amount of bleeding during operation was(192.32±9.65)ml,all were significantly lower than those in the control group[the hospitalization time was(21.76±3.23)days,the indwelling time of urinary catheter was(35.88±4.22)hours,the exhaust time after operation was(54.01±6.98)hours,and bleeding volume during operation was(429.80±17.98)ml](all P<0.05).The incidence of postoperative complications in the observation group(7.50%)was significantly lower than that in the control group(35.00%)(P<0.05).During the follow-up period,no recurrence or death occurred,but one patient in the control group had lymph node metastasis,the metastasis rate was 2.50%,and there was no significant difference between the two groups(P>0.05).Conclusion:For early cervical cancer patients,laparoscopic radical resection of cervical cancer can significantly increase the number of resected lymph nodes,reduce intraoperative bleeding,shorten the time of urinary catheter indwelling and exhaust after operation,and the incidence of postoperative complications is low,so it has high clinical value.
作者 陶玲 努尔孜燕·力提甫 周琦 TAO Ling;Nuerziyan·LITIFU;ZHOU Qi(Affiliated Tumor Hospital of Xinjiang Medical University,Urumqi 830011,China)
出处 《陕西医学杂志》 CAS 2021年第2期148-150,161,共4页 Shaanxi Medical Journal
基金 国家自然科学基金资助项目(81272335) 新疆维吾尔自治区自然科学基金资助项目(2019D01C247)。
关键词 早期子宫颈癌 治疗 腹腔镜下宫颈癌根治术 淋巴结清除数目 临床疗效 Early cervical cancer Therapy Laparoscopic radical hysterectomy for cervical cancer Number of lymph node dissection Clinical efficacy
作者简介 通讯作者:周琦,E-mail:19772230@qq.com。
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