摘要
脑胶质瘤是中枢神经系统常见的一类恶性肿瘤,经术后或其他方式治疗后极易复发,复发后的脑胶质瘤,其组织学分化的恶性特征较前明显、恶性程度增加、侵袭力更强,且治疗效果差,生存期短。但其复发后仍无标准的治疗方式,现在主要的治疗方式有手术、放疗、化疗、靶向治疗、免疫治疗等,本文就近年来关于复发脑胶质瘤在病因学、临床特征、病理学、分子诊断和治疗策略等几个方面的进展做一综述。
Glioma is a common malignant tumor of nervous system.After recurrence of glioma,its histological differentiation is more malignant than before,with increased degree of malignancy,stronger invasion ability,poor treatment effect,and short survival time.There is no standard treatment after recurrence.The main treatment methods include secondary surgery,radiotherapy,chemotherapy,targeted therapy,immunotherapy.This article reviews the recent advances in etiology,clinical features,pathology,molecular diagnosis and treatment strategies of recurrent gliomas.
作者
何远秀
钟文君
李悦(综述)
邹彦(审校)
HE Yuan-xiu;ZHONG Wen-jun;LI Yue;ZOU Yan(Department of Head and Neck Oncology,the Second Affiliated Hospital of Zunyi Medical University,Zunyi 563000,Guizhou,CHINA;Department of Geriatrics,Chongqing Bishan District People's Hospital,Chongqing 402760,CHINA)
出处
《海南医学》
CAS
2021年第2期246-249,共4页
Hainan Medical Journal
关键词
复发脑胶质瘤
分子诊断
再程手术
放疗
化疗
靶向治疗
Recurrent gliomas
Molecular diagnosis
Reoperation
Radiotherapy
Chemotherapy
Targeted therapy
作者简介
通讯作者:邹彦,主任医师,教授,硕士研究生导师,E-mail:zouyan.714@163.com。
