摘要
目的:研究针灸联合健脾补肾汤对多囊卵巢综合征(PCOS)患者卵巢功能、代谢紊乱的影响。方法:选取本院收治的PCOS患者100例,按照完全随机法将患者分为健脾补肾汤组、联合组各50例。健脾补肾汤组给予健脾补肾汤;联合组在健脾补肾汤组的基础上给予针灸治疗。检测促卵泡激素(FSH)、睾酮(T)、垂体泌乳素(PRL)、雌二醇(E2)、空腹胰岛素(FIN)、空腹血糖(FBG)、胰岛素抵抗指数(HOMA-IR)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、子宫内膜厚度、卵巢体积、卵巢窦卵泡数目、C反应蛋白(CRP)、降钙素原(PCT),比较治疗有效率。结果:联合组治疗后FSH、T、PRL、FIN、FBG、HOMA-IR、TG、TC及LDL-C低于健脾补肾汤组,E2、HDL-C水平高于健脾补肾汤组(P<0.05)。联合组治疗后子宫内膜厚度高于健脾补肾汤组,卵巢体积、卵巢窦卵泡数目低于健脾补肾汤组(P<0.05)。联合组治疗后CRP、PCT水平低于健脾补肾汤组(P<0.05)。联合组治疗后总有效率高于健脾补肾汤组(P<0.05)。结论:针灸联合健脾补肾汤对PCOS患者治疗效果显著,有效提高患者卵巢功能,改善内分泌代谢紊乱,降低炎症反应,值得临床推广。
Objective:To study the effects of acupuncture combined with Jianpi Bushen Decoction on ovarian function and metabolic disorders in patients with polycystic ovary syndrome(PCOS).Methods:A total of 100 PCOS patients admitted in our hospital from October 2018 to January 2020 were selected,and the patients were divided into the Jianpi Bushen Decoction group and the combined group with 50 patients each according to a completely random method.The patients in the Jianpi Bushen Decoction group were given Jianpi Bushen Decoction;the combined group was given acupuncture on the basis of the Jianpi Bushen Decoction group.Detection of follicle stimulating hormone(FSH),testosterone(T),pituitary prolactin(PRL),estradiol(E2),fasting insulin(FIN),fasting blood glucose(FBG),insulin resistance index(HOMA-IR),triglyceride Ester(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),endometrial thickness,ovarian volume,number of ovarian sinus follicles,C-reactive protein(CRP),procalcitonin(PCT).Statistical treatment is effective.Results:After treatment,FSH,T,PRL,FIN,FBG,HOMA-IR,TG,TC and LDL-C were lower in Jianpi Bushen Decoction group,and E2 and HDL-C levels were higher than Jianpi Bushen Decoction group(P<0.05).The endometrial thickness of the combined group was higher than that of Jianpi Bushen Decoction group,and the ovarian volume and the number of ovarian sinus follicles were lower than that of Jianpi Bushen Decoction group(P<0.05).The levels of CRP and PCT in the combination group were lower than those in the Jianpi Bushen Decoction group(P<0.05).The total effective rate of patients in combination group was higher than that in Jianpi Bushen Decoction group(P<0.05).Conclusion:Acupuncture combined with Jianpi Bushen Decoction has significant therapeutic effects on patients with PCOS,effectively improves patients'ovarian function,improves endocrine and metabolic disorders,and reduces inflammatory reactions,which deserves clinical promotion.
作者
柴洪佳
逯芳芳
余璟玮
郑泳霞
杜嫦燕
CHAI Hong-jia;LU Fang-fang;YU Jing-wei;ZHENG Yong-xia;DU Chang-yan(Department of TCM Gynecology,Panyu Material and Child Health Hospital of Guangzhou(Panyu He Xian Memorial Hospital of Guangzhou),Guangdong 511400,China)
出处
《海南医学院学报》
CAS
2021年第2期111-115,120,共6页
Journal of Hainan Medical University
基金
广东省中医药局科研项目(20191265)。
关键词
针灸
健脾补肾汤
多囊卵巢综合征
卵巢功能
Acupuncture
Jianpi Bushen Decoction
Polycystic ovary syndrome
Ovarian function
作者简介
柴洪佳(1981-),女,硕士,副主任医师,电话15323347925,E-mail:chaidoc08@163.com。
