摘要
目的系统回顾有关营养素、食物和膳食模式对机体炎症因子或氧化应激标记物水平的影响。方法以营养素、食物、膳食、膳食结构、膳食模式、蛋白质、脂肪、维生素、膳食纤维、炎症、炎性、氧化应激、免疫力、免疫等作为中文检索词,以nutrients、nutrition、food、diet、dietary structure、dietary patterns、protein、fat、vitamin、dietary fiber、immune、immunity、inflammatory、inflammation、oxidative stress等作为英文检索词,分别对万方数据库、中国知网、PubMed和Web of Science等数据库从建库至2020年1月10日收录文献进行系统检索,对符合要求的文献进行系统综述。结果共纳入3篇中文文献和46篇英文文献。β-胡萝卜素、维生素C、维生素D、多不饱和脂肪酸、部分氨基酸、膳食纤维、异黄酮、胆碱、甜菜碱和白藜芦醇等营养素可降低血浆炎症因子或氧化应激标记物水平,而胆固醇、反式脂肪酸等营养素则可升高其水平。鱼类、精瘦肉、水果、大豆、十字花科蔬菜和坚果等食物可降低血浆炎症因子或氧化应激标记物水平,而牛奶、含糖饮料等食物可提高其水平。地中海膳食模式和其他健康化膳食模式均可降低血浆炎症因子或氧化应激标记物水平,而西方膳食模式可升高其水平。结论营养素、食物和膳食模式均可对血浆炎症因子或氧化应激标记物水平产生影响。
Objective To systematically review the effects of nutrients,food and diet patterns on markers of inflammation and oxidative stress.Methods Nutrients,nutrition,food,diet,dietary structure,dietary patterns,protein,fat,vitamin,dietary fiber,inflammatory,inflammation,oxidative stress,immunity were used as search terms,and systematic retrieval of the literature in Wanfang Database,National Knowledge Infrastructure(CNKI),PubMed,Web of Science was carried out from the establishment of the database to January 10,2020,and a systematic review of the literature meeting the requirements was conducted.Results A total of 3 Chinese and 46 English articles were included.Literature showed that β-carotene,vitamin C,vitamin D,polyunsaturated fatty acids,some amino acids,dietary fiber,isoflavones,choline,betaine and resveratrol and other nutrients can reduce plasma inflammatory factors or oxidative stress marker levels,and nutrients such as cholesterol and trans fatty acids can increase their levels.Foods such as fish,lean meat,fruits,soybeans,cruciferous vegetables and nuts can reduce plasma inflammatory factors or oxidative stress marker levels,while foods such as milk and sugary beverages can increase plasma inflammatory factors or oxidative stress markers.Mediterranean dietary patterns and other healthy dietary patterns can reduce plasma levels of inflammatory factors or oxidative stress markers,while Western dietary patterns can increase their levels.Conclusion Nutrients,food and dietary patterns can influence levels of plasma inflammatory factors or oxidative stress markers.
作者
丁心悦
刘开琦
赵文华
Ding Xinyue;Liu Kaiqi;Zhao Wenhua(National Institute for Nutrition and Health,Chinese Center for Disease Control and Prevention,Beijing 100050,China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2020年第48期3897-3902,共6页
National Medical Journal of China
基金
中国工程院课题咨询研究项目(2018-ZD-09-03)。
关键词
膳食
营养评价
炎症
氧化性应激
系统综述
Diet
Nutrition assessment
Inflammation
Oxidative stress
Systematic review
作者简介
通信作者:赵文华,Email:zhaowh@chinacdc.cn。
