摘要
新生儿败血症为新生儿时期病情严重的感染性疾病,其具有发病急骤、病情进展迅速、死亡率高的特点。而早产儿因其病理生理变化及解剖结构的特殊性,更易引起早产儿败血症的发生,给早产儿带来永久性损伤,严重者甚至死亡。因此,临床需早期识别早产儿败血症,并了解败血症早产儿血液指标及胃肠道菌群的改变。基于此,本研究对近阶段关于早产儿败血症外周血调节性B细胞(Breg细胞)和肠道菌群动态变化特征及机制相关的文献进行收集并总结,以期为临床合理诊断及治疗早产儿败血症提供一定的参考价值。
Neonatal septicemia is a serious infectious disease in neonatal period,which has the characteristics of acute onset,rapid disease progression and high mortality.Premature infants are more likely to cause septicemia due to the physiological changes and the special anatomical structure of their cases,which will cause permanent damage to premature infants and even death in severe cases.Therefore,it is of great significance to recognize sepsis in premature infants and to understand the changes of blood indicators and gastrointestinal flora in premature infants with sepsis.Based on it,this study collected and summarized the literatures related to the dynamic changes of Breg cells and intestinal flora in peripheral blood of premature sepsis in the recent stage,so as to provide certain reference value for rational clinical diagnosis and treatment of premature sepsis.
作者
陈泽斌
CHEN Zebin(Maternal and Child Health Care Family Planning Service Center,Tianhe District,Guangzhou,Guangdong 510665,China)
出处
《大医生》
2020年第18期106-107,共2页
Doctor
关键词
早产儿
败血症
Breg细胞
肠道菌群
变化特征
机制
premature infants
sepsis
breg cells
intestinal flora
change characteristics
mechanism
作者简介
陈泽斌,本科,主治医师,研究方向:儿科及新生儿科常见病、多发病的诊治。
