摘要
炎症性肠病(IBD)是一种反复发作的慢性非特异性肠道炎症性疾病。由于IBD导致患者营养状况下降、免疫功能紊乱以及治疗需应用激素、免疫抑制剂,因此,IBD患者是机会性感染的高风险人群。EB(Epstein-Barr)病毒作为一种机会致病病毒,在IBD患者中较为常见。EB病毒感染可导致IBD患者病情进展迅速、对常规药物治疗反应差,并诱发可能与EB病毒相关的淋巴组织增殖性疾病。本文从IBD患者合并EB病毒感染的流行病学、危险因素、诊断、治疗策略等方面进行分析论述。
Inflammatory bowel disease(IBD)is a recurrent chronic non-specific intestinal inflammatory disease.Because of the poor nutritional status and immune dysfunction caused by IBD,and the therapeutic application of glucocorticoid and immunosuppressive agents in some patients,the IBD patients are at high risk of opportunistic infections.Epstein-Barr virus(EBV)is a kind of opportunistic causative virus which is common in IBD patients.EBV infection can cause the rapid disease progresses,worsen the effect of conventional medicine treatment,and induce the EBV-associated lymphoproliferative disorders.This article discusses the epidemiology,risk factors,clinical characteristics and the therapeutic strategies of IBD patients with EBV infection.
作者
赵丹丹
尹凤荣
郭金波
张晓岚
Zhao Dandan;Yin Fengrong;Guo Jinbo;Zhang Xiaolan(Department of Gastroenterology,The Second Hospital of Hebei Medical University,Hebei Key Laboratory of Gastroenterology,Hebei Institute of Gastroenterology,Shijiazhuang 050000,China)
出处
《中华炎性肠病杂志（中英文）》
2020年第4期292-297,共6页
Chinese Journal of Inflammatory Bowel Diseases
关键词
炎症性肠病
EB病毒
危险因素
诊断
治疗策略
Inflammatory bowel disease
Epstein-Barr virus
Risk factors
Diagnosis
Therapeutic strategies
作者简介
通信作者:张晓岚,Email:xiaolanzh@126.com,电话:0311-66007370。
