摘要
选取宫颈癌患者122例作为研究对象,根据病理检查结果分为发生腹膜后淋巴结转移患者(转移组,28例)和未发生腹膜后淋巴结转移患者(未转移组,94例),均行全腹CT检查和血清肿瘤标志物癌胚抗原(CEA)、癌抗原125(CA125)、鳞状细胞癌抗原(SCC-Ag)检测。结果发现,转移组患者CT横轴位淋巴结最短径均值长于未转移组,血清CEA、CA125、SCC-Ag水平均高于未转移组,差异具有显著性。转移组患者血清CEA、CA125、SCC-Ag水平与CT横轴位淋巴结最短径呈正相关,诊断腹膜后淋巴结转移的AUC值大小顺序为:CT检查联合血清肿瘤标志物>CT横轴位淋巴结最短径>SCC-Ag>CEA>CA125。本文结果证实,CT检查联合血清肿瘤标志物可为临床术前评估是否存在腹膜后淋巴结转移提供较为准确的依据。
122 cases of cervical cancer patients were selected as the research object.According to the results of pathological examination,they were divided into metastasis group(28 patients with retroperitoneal lymph node metastasis)and non-metastasis group(94 patients without retroperitoneal lymph node metastasis).All of them were subjected to CT examination of the whole abdomen and detection of serum tumor markers including carcinoembryonic antigen(CEA),cancer antigen 125(CA125)and squamous cell carcinoma antigen(SCC-Ag).The results showed that the shortest diameter of CT lymph nodes in the metastatic group was longer than that in the non-metastatic group,and the levels of serum CEA,CA125 and SCC-Ag were higher than those in the non-metastatic group(P<0.05).Serum CEA,CA125,SCC-Ag levels were positively correlated with the shortest diameter of the lymph nodes in the horizontal axis of CT,and the sequence of AUC value for diagnosis of retroperitoneal lymph node metastasis was:CT combined with serum tumor markers>the shortest diameter of CT lateral axis lymph node>SCC-Ag>CEA>CA125.It can provide an objective basis for clinical preoperative evaluation of the presence of retroperitoneal lymph node metastasis.
作者
韩茜茜
卜岛
HAN Qianqian;BU Dao(Department of Radiology,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing 100026,P.R.China)
出处
《影像科学与光化学》
CAS
2020年第6期982-987,共6页
Imaging Science and Photochemistry
关键词
CT
宫颈癌
腹膜
淋巴结转移
癌胚抗原
鳞状细胞癌抗原
癌抗原125
CT
cervical cancer
peritoneum
lymph nodes metastasis
carcinoembryonic antigen
squamous cell carcinoma antigen
cancer antigen 125
作者简介
通讯作者:韩茜茜。
