摘要
为了解母猪哺乳期猪瘟抗体变化和母源抗体水平对仔猪免疫效果影响,采用ELISA方法分别对40头母猪哺乳前后猪瘟抗体水平和13窝仔猪28日龄母源抗体水平进行检测,同时选择6窝仔猪跟踪检测了首免和二免后猪瘟抗体变化.结果显示:一个哺乳期母猪猪瘟抗体呈现不同程度下降,但抗体阻断率高于70%的母猪降幅度要小于阻断率低于70%的母猪;仔猪28日龄的母源抗体水平和母猪分娩当天抗体水平呈正相关;当仔猪母源抗体阻断率高于60%时,严重影响猪瘟疫苗免疫效果.研究结果表明,母猪群猪瘟抗体水平对商品猪群免疫效果影响明显,高效价和低离散度的母猪群抗体是商品猪群制定合理免疫程序和确保免疫效果的基础.
In order to understand the lactation period sows changes of antibody to CSFV and the influence of maternal antibody level on the immune effect of piglets,an experiment was conducted to 40 sows and 13 litters of piglets.The antibody levels of 40 sows before and after lactation and the maternal antibody levels of 13 litters of piglets at 28 days old were detected by ELISA.Meanwhile,6 litters of piglets were selected to track the antibody changes after the first and second immunization.The tests data showed that the antibody level of a suckling period sows decreased in varying degrees,but the antibody blocking rate over 70%sows drop smaller than under 70%sows;there was a positive correlation between the maternal antibody level of piglets at 28 days old and the antibody level of sows at the day of farrowing;when the antibody blocking rate of piglets was higher than 60%,the immune effect of swine fever vaccine was seriously affected.The research results showed that the antibody level of sows had a significant effect on the immune effect of commercial swine herd.High level and low dispersion of sows antibody is the basis of developing proper immune procedure and ensuring immune effect for commercial pigs.
作者
南文金
黄健强
吴静波
胡鸿惠
钟澜
陈细浩
彭国良
NAN Wen-jin;HUANG Jian-qiang;WU Jing-bo;HU Hong-hui;ZHONG Lan;CHEN Xi-hao;PENG Guo-liang(Northern Guangdong Province Research Center For Pig Breeding Waste Reduction Engineering Technology,Shaoguan University,Shaoguan 512005,Guangdong,China;Animal Husbandry Research Institute of Shaoguan,Shaoguan 512005,Guangdong,China)
出处
《韶关学院学报》
2020年第9期39-44,共6页
Journal of Shaoguan University
基金
广东省自然科学基金项目(2018A0303070007)
韶关市科技计划项目(韶科[2017]62号).
关键词
母猪
仔猪
猪瘟
抗体水平
免疫效果
sow
piglet
classical swine fever
antibody level
immune effect
作者简介
南文金(1981-),男,河南灵宝人,韶关学院广东省粤北生猪养殖废弃物减量化工程技术研究中心助理研究员,硕士,研究方向:动物疫病防控技术;通讯作者:彭国良.
