摘要
目的运用Meta分析方法综合定量评价中国人群慢性疲劳综合征(chronic fatigue syndrome,CFS)的患病率。方法计算机检索中国期刊全文数据库、万方数据知识服务平台、维普期刊中文服务平台、中国生物医学文献数据库、PubMed、Embase、Web of Science、CENTRAL和CINAHL数据库,收集关于中国人群CFS患病率的研究,检索时限为建库至2020年2月。由2位研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 15.1软件进行Meta分析。结果最终纳入37篇文献,包括61 833例研究对象,5189名CFS患者,Meta分析结果显示:中国人群CFS的患病率为12.54%[95%CI(8.64%~17.04%)]。按性别进行亚组分析,男性和女性的患病率分别为13.01%和14.21%;按地区进行亚组分析,西部地区为15.27%,中部地区为14.80%,东部地区为10.09%,东北部地区为14.84%;按学段进行亚组分析,初中生、高中生、大学生患病率分别为9.22%、9.53%、13.38%;按年龄进行亚组分析,小于30岁、30~40岁、41~50岁及50岁以上的患病率分别为14.63%、21.57%、13.04%、14.81%;按调查场所进行亚组分析,在学校进行的与在医院进行的患病率分别为12.77%、15.45%;按诊断标准进行亚组分析,采用CDC制定的CFS诊断标准与日本厚生省制定的CFS诊断标准的患病率分别为12.21%和13.31%;按职业/身份进行亚组分析,教师、学生、医护人员、职员、工人、军人的患病率分别为18.95%、8.84%、13.89%、1.64%、1.57%、28.93%;按发表时间进行亚组分析,1998年~2000年为12.27%、2001年~2010年为9.72%、2011年~2019年为14.31%。结论我国的慢性疲劳综合征患病率较高,不同性别、地区、学龄层次、年龄、调查场所、诊断标准、职业/身份及不同发表时间的慢性疲劳综合征患病率存在差异。
Objective To estimate the prevalence of chronic fatigue syndrome(CFS)in China comprehensively by Meta-analysis.Methods Chinese Journal Full-text Database(CJFD),Wanfang Data Knowledge Service Platform,VIP Chinese Journal Service Platform,China Biology Medicine disc(CBMdisc),PubMed,Embase,Web of Science,CENTRAL and CINAHL were searched to collect studies on the prevalence of CFS in China.And the time limit of researches was from the establishment of these databases to February 2020.Two reviewers independently screened literatures,extracted data and evaluated risk of bias of the included studies,then Meta-analysis was performed by Stata 15.1 software.Results A total of 37 studies were involved,including 61833 participants and 5189 CFS patients.The results of Meta-analysis showed that the prevalence of CFS in Chinese population was 12.54%[95%CI(8.64%-17.04%)].Subgroup analysis according to genders showed that the prevalence of male and female was13.01%and 14.21%,respectively.Subgroup analysis according to regions showed that the prevalence of western region,central region,eastern region and northeast region was 15.27%,14.80%,10.09%,and 14.84%,respectively.Subgroup analysis according to school stages showed that the prevalence of middle school students,high school students and college students was 9.22%,9.53%and 13.38%,respectively.Subgroup analysis according to ages showed that the prevalence of patients younger than 30 years old,30-40 years old,41-50 years old and over 50 years old was 14.63%,21.57%,13.04%and 14.81%,respectively.Subgroup analysis according to investigation places showed that the prevalence in schools and hospitals was 12.77%and 15.45%,respectively.Subgroup analysis according to diagnostic criteria showed that the prevalence of the CFS diagnostic criteria formulated by the CDC and the CFS diagnostic criteria formulated by the Ministry of Health of Japan was 12.21%and 13.31%,respectively.Subgroup analysis according to occupations/identities showed that the prevalence of teachers,students,medical staff,staff,workers and soldiers was 18.95%,8.84%,13.89%,1.64%,1.57%and 28.93%,respectively.Subgroup analysis according to publishing time showed that the prevalence published from 1998 to 2000,from 2001 to 2010,from 2011 to 2019 was 12.27%,9.72%,14.31%,respectively.Conclusion The prevalence of chronic fatigue syndrome is high in China,and it varies with genders,regions,school stages,ages,investigation places,diagnostic criteria,occupations/identities and publishing time.
作者
伍侨
高静
柏丁兮
钟懿珠
杨直
江小林
郑雨萍
WU Qiao;GAO Jing;BAI Dingxi;ZHONG Yizhu;YANG Zhi;JIANG Xiaolin;ZHENG Yuping(School of Nursing,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan,China)
出处
《右江医学》
2020年第10期727-735,共9页
Chinese Youjiang Medical Journal
基金
四川省科技计划项目(2018SZ0376)。
作者简介
伍侨,女,护士,理学学士,在读硕士研究生,研究方向:护理学。E-mail:1952244025@qq.com;通信作者:高静。E-mail:729012934@qq.com。
