摘要
目的探讨子宫肌瘤微创术后泌尿系感染的病原菌分布及血清超敏C-反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、降钙素(PCT)的早期预测价值。方法选取2016年1月-2018年12月在本院治疗的子宫肌瘤微创术后泌尿系感染者78例作为感染组,同时选取子宫肌瘤微创术未感染患者75例作为对照组,检测子宫肌瘤微创术后泌尿系感染的病原菌分布;检测2组血清hs-CRP、TNF-α、PCT表达水平。结果研究发现子宫肌瘤微创术后泌尿系感染的病原菌主要为革兰阴性菌;子宫肌瘤微创术后泌尿系感染患者血清内hs-CRP、TNF-α、PCT表达水平明显高于对照组(P<0.05);同时发现对hs-CRP、TNF-α、PCT三者联合诊断的特异性、灵敏性均高于单项检查(P<0.05)。结论子宫肌瘤微创术后应及时给予抗菌药物,预防感染的发生,同时密切关注患者血清hs-CRP、TNF-α、PCT的表达水平,提早判断感染的发生。
Objective To investigate the distribution of pathogenic bacteria in urinary tract infection after minimally invasive surgery for uterine leiomyoma and the early predictive value of serum high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α)and calcitonin(PCT).Methods 78 cases of urinary tract infection after minimally invasive hysteromyoma surgery in our hospital from January 2016 to December 2018 were selected,and 75 cases of non-invasive hysteromyoma surgery were selected as control group.The distribution of pathogenic bacteria in urinary tract infection after minimally invasive hysteromyoma surgery was detected;the levels of hs-CRP,TNF-α,PCT in serum of the two groups were detected;and the correlation of serum LDL-C,Hcy and TG levels was detected.Results Gram-negative bacteria were the main pathogens of urinary tract infection after minimally invasive surgery for uterine leiomyoma.The levels of hs-CRP,TNF-αand PCT in serum of patients with urinary tract infection after minimally invasive surgery for uterine leiomyoma were significantly higher than those of control group(P<0.05),and the specificity and sensitivity of combined diagnosis of hs-CRP,TNF-αand PCT were higher than those of single examination(P<0.05).Conclusion Antibiotics should be given in time to prevent infection after minimally invasive surgery of uterine leiomyoma.At the same time,the levels of hs-CRP,TNF-αand PCT in serum of patients should be closely monitored,and the occurrence of infection should be judged early.
作者
徐小娟
周胤婵
范丽英
洪文忠
XU Xiao-juan;ZHOU Yin-chan;FAN Li-ying;HONG Wen-zhong(Department of Operation Room,the First People's Hospital of Chun'an County,Hangzhou,Zhejiang 311700,China;不详)
出处
《中国卫生检验杂志》
CAS
2020年第18期2221-2223,共3页
Chinese Journal of Health Laboratory Technology
作者简介
徐小娟(1982-),女,本科,主管护师,主要从事泌尿方面的研究工作。
