摘要
目的比较QCT与DXA在藏族、汉族患者骨密度评估中的差异,探讨DXA、QCT在藏族骨质疏松患者中的临床价值。方法收集2018年12月至2019年9月期间在我院同时行腰椎DXA及腰椎QCT检查的患者一般诊疗信息及DXA、QCT检查结果,同时有经验丰富的影像科医师通过腰椎CT影像对椎体及相近附件行影像学诊断。正态性分布的计量资料以均数±标准差表示,组间比较独立样本t检验,率的比较采用Fisher确切概率法。结果藏族平均腰椎DXA T值高于汉族(-0.19±2.44 vs-1.17±1.40,P<0.05),但藏、汉两族QCT骨量差异无统计学意义(71.51±24.10 mg/cm^3 vs 75.31±25.01 mg/cm^3)。在藏族、汉族患者中QCT检出骨质疏松的例数均多于DXA,差异有统计学意义(P=0.004);慢性肾脏疾病患者DXA表现为高T值同时QCT可为正常骨量。结论对于体型肥胖、合并椎体退行性变或慢性肾脏疾病的患者应选用QCT评估其骨密度,较DXA,QCT能更为准确地评估藏族患者骨密度。
Objective To compare the difference of bone mineral density measurement between lumbar quantitative CT(QCT)and DXA in Tibetans and Han nationality,and to discuss clinic value of QCT and DXA in Tibetan patients.Methods General character information and DXA,QCT reports were collected at Hospital of Chengdu Office of People's Government of Tibetan from December 2018 to September 2019.The imaging diagnosis of these patients was performed by experienced radiologists through lumbar CT images.Normal distribution data were showed as mean and standard deviation.The t test was used for the comparison of independent samples between the groups.Fisher’s exact probability calculation method was used to compare the sample rate between the groups.Results The average DXA T value in Tibetan patients was higher than that in Han patients(-0.19±2.44 vs.-1.17±1.40,P<0.05).However,there was no significant difference of BMD between Tibetan and Han patients measured with QCT(71.51±24.10 vs.75.31±25.01 mg/cc).The number of cases of osteoporosis detected with QCT was more than that with DXA,and the difference was statistically significant(P=0.004).In patients with chronic kidney disease,DXA showed high T values while QCT showed normal bone mass.Conclusion For patients with obesity,vertebral degeneration,or chronic kidney disease,QCT should be used to evaluate their BMD.BMD is more accurately evaluated by QCT than by DXA in Tibetan patients.
作者
郭彦宏
邬云红
王溯源
何万林
李相位
黄伦浪
李明霞
程晓光
GUO Yanhong;WU Yunhong;WANG Suyuan;HE Wanlin;LI Xiangwei;HUANG Lunlang;LI Mingxia;CHENG Xiaoguang(Department of Endocrinology,Hospital of Chengdu Office of People’s Government of Tibetan Autonomous Region,Chengdu 610000,China;Department of Radiology,Hospital of Chengdu Office of People’s Government of Tibetan Autonomous Region,Chengdu 610000,China;Department of Radiology,Beijing Jishuitan Hospital,Beijing 100035,China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2020年第9期1340-1343,共4页
Chinese Journal of Osteoporosis
作者简介
通信作者:程晓光,Email:xiao65@263.net。
