摘要
目的:探讨单侧甲状腺乳头状癌颈部中央区淋巴结转移的临床特点及影响因素。方法:选择2015年3月-2019年3月攀枝花市中心医院收治的单侧甲状腺乳头状癌患者179例,观察颈部中央区淋巴结转移发生情况。采用单因素分析影响颈部中央区淋巴结转移相关因素;多因素Logistic回归分析影响颈部中央区淋巴结转移危险因素。收集资料包括性别、年龄、吸烟史、饮酒史、合并基础疾病、肿瘤直径、原发病灶、形态、边界、包膜侵犯。结果:单侧甲状腺乳头状癌患者179例,发生颈部中央区淋巴结转移56例,占31.28%;未发生颈部中央区淋巴结转移123例,占68.72%。单因素分析结果显示,两组性别、年龄、吸烟史、饮酒史、合并基础疾病、形态和边界比较差异无统计学意义(P>0.05);两组肿瘤直径、多发病灶和包膜侵犯比较差异有统计学意义(P<0.05)。将上诉单因素分析差异有统计学意义的因素纳入多因素Logistic回归分析,肿瘤直径、多发病灶和包膜侵犯为影响颈部中央区淋巴结转移的危险因素。结论:单侧甲状腺乳头状癌颈部中央区淋巴结转移发生率较高,颈部中央区淋巴结转移受多因素影响,其中肿瘤直径、多发病灶和包膜侵犯为其危险因素。
Objective:To investigate the clinical characteristics and influencing factors of lymph node metastasis in the neck of unilateral papillary thyroid carcinoma.Methods:From March 2015 to March 2019,179 patients with unilateral papillary thyroid cancer were selected from Panzhihua central hospital to observe the incidence of lymph node metastasis in the central region of the neck.Single factor analysis was used to analyze the factors related to lymph node metastasis in the central region of the neck;multi factor Logistic regression analysis was used to analyze the risk factors of lymph node metastasis in the central region of the neck.The data collected included sex,age,smoking history,drinking history,combined basic diseases,tumor diameter,primary focus,shape,boundary and capsule invasion.Results:Among 179 patients with unilateral papillary thyroid carcinoma,56(31.28%)had lymph node metastasis in the central region of the neck,and 123(68.72%)had no lymph node metastasis in the central region of the neck.The results of univariate analysis showed that there were no significant differences between the two groups in gender,age,smoking history,drinking history,combined basic diseases,shape and boundary(P>0.05);there were significant differences in tumor diameter,multifocal and capsule invasion between the two groups(P<0.05).The factors with statistical significance were included in the multiple factor Logistic regression analysis.Tumor diameter,primary focus and capsule invasion were the risk factors for lymph node metastasis in the central region of the neck.Conclusion:The incidence of cervical lymph node metastasis in unilateral papillary thyroid carcinoma is high.The cervical lymph node metastasis was analyzed by multiple factors,including tumor diameter,primary focus and capsule invasion.
作者
罗杰
耿成义
罗斌
LUO Jie;GENG Cheng-yi;LUO Bin(Department of General Surgery,Panzhihua Central Hospital,Panzhihua 617000,China)
出处
《中国现代普通外科进展》
CAS
2020年第9期704-707,共4页
Chinese Journal of Current Advances in General Surgery
关键词
甲状腺乳头状癌
单侧
颈部中央区淋巴结转移
临床特点
影响因素
Papillary thyroid carcinoma
Unilateral
Central cervical lymph node metastasis
Clinical characteristics and influencing factors
作者简介
罗杰(1985-12-),男,四川泸州人,硕士,主治医师,研究方向:胃肠及甲状腺、乳腺。E-mail:skyssws@126.com。
