摘要
高危药品的药理作用显著且迅速,使用不当极易发生严重后果甚至危害生命,故加强高危药品的风险管理对减少用药差错、降低不良事件发生率有重要意义。医疗机构高危药品风险管理的核心是控制高危药品在医疗机构内部流通过程中对患者产生危害的可能性,目前国内大多数医疗机构使用失效模式和效应分析(FMEA)来进行高危药品的风险管理。随着医药科学技术的高速发展和医疗卫生体制的变革,FMEA已经无法满足于高危药品全面、精准的管理,研究者们开始探索高危药品风险管理的新技术和新方法,其中社会技术概率风险评估(ST-PRA)是一种可同时纳入人为和技术因素,并将风险量化的方法,但其在国内的应用尚不成熟。该文详细阐述FMEA和ST-PRA方法在高危药品风险管理中的应用,并对其进行总结和比较,以期为更科学、有效地开展高危药品风险管理时选择研究方法提供依据。
The pharmacological effects of high-risk drugs are significant and rapid.Improper use can easily lead to serious consequences or even life-threatening condition.In order to reduce the occurrence of drug errors and the incidence of adverse events,it is great significance to strengthen the management of high-risk drugs.The core of high-risk drugs management in healthcare institutions is to control the possibility of high-risk drugs which cause harm to patients during the internal circulation.At present,most healthcare institutions in China use failure mode and effect analysis(FMEA)to carry out high-risk drugs management.With the rapid development of technology and the reform of health care system,FMEA has been unable to meet the comprehensive and precise management of high-risk drugs,and researchers have begun to explore new technologies and methods for the management of high-risk drugs.Among them,sociotechnical probabilistic risk assessment(ST-PRA)can incorporate human,technical factors,and risks quantification simultaneously.But it did not have a very mature application in high-risk drugs management in China.Therefore,this study elaborates and compares the application of FMEA and ST-PRA methods in high-risk drugs management to provide a basis for scientific and effective selection of research methods for high-risk drugs management.
作者
上官小芳
柯萌
杨林慧
刘雨鑫
王佳
蔡沅璇
黄锐
张程亮
SHANGGUAN Xiaofang;KE Meng;YANG Linhui;LIU Yuxin;WANG Jia;CAI Yuanxuan;HUANG Rui;ZHANG Chengliang(School of Pharmacy,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Health Bureau of Hanbin District of Ankang City,Shannxi Province,Ankang 725000,China;Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)
出处
《医药导报》
CAS
北大核心
2020年第10期1350-1355,共6页
Herald of Medicine
基金
国家自然科学基金资助项目(71503089)。
作者简介
上官小芳(1994-),女,福建泉州人,在读硕士,研究方向:药事管理学、药品安全。ORCID:0000-0002-4790-1856,电话:027-83692762,E-mail:shangguan.xf@foxmail.com;通信作者:黄锐(1981-),男,安徽宣城人,副教授,博士,研究方向:药事管理学、药品安全。电话:027-83692762,E-mail:hys19810612@163.com;通信作者:张程亮(1981-),男,河北井陉人,副教授,博士,研究方向:药物流行病学。电话:027-83663519,E-mail:clzhang@tjh.tjmu.edu.cn。
