摘要
目的比较青年与老年2型糖尿病心血管疾病(CVD)发生风险。方法研究人群来源于内蒙古医科大学附属医院2013年1月1日至2014年1月1日收治的糖尿病患者,采用系统抽样方法选取924例2型糖尿病患者,其中485例青年(18~40岁)2型糖尿病患者,439例老年(>60岁)2型糖尿病患者。参考CVD风险评估测量模型,采用横断面研究方法对所选取患者的高血压、肥胖[体质量指数(BMI)>25 kg/m2]、高血糖、高胆固醇血症等CVD因素进行比较,随访至2019年1月1日,观察两组患者发生CVD风险。结果青年与老年2型糖尿病患者糖化血红蛋白(HbA1c)、BMI、收缩压、舒张压、总胆固醇、低密度脂蛋白水平均无统计学意义(P>0.05),且CVD风险因素高血压、肥胖、高血糖、高胆固醇血症比较差异无统计学意义(P>0.05)。青年和老年2型糖尿病患者无CVD风险因子、一个风险因素、两个风险因素、三个风险因素、四个风险因素累加比例均无统计学意义(P>0.05)。两组随访结束时CVD例数、随访5年时CVD例数、两个CVD例数、两个以上CVD例数差异均无统计学意义(P>0.05)。结论青年2型糖尿病患者发生CVD风险并不低于老年患者。
Objective To compare the risk of cardiovascular disease(CVD)in young and elderly type 2 diabetes.Methods The study population were derived from Affiliated Hospital of Inner Mongolia medical university from January 1,2013 to January 1,2014.A systematic sampling method was used to select 924 patients with type 2 diabetes,of which 485 were young patients(18-40 years old),439 were elderly patients(>60 years old).Referring to the CVD risk assessment measurement model,cross-sectional study was used to compare the CVD factors such as hypertension,obesity[body mass index(BMI)>25 kg/m2],hyperglycemia and hypercholesterolemia in the patients.The follow-up continued to January 1,2019,and the risk of CVD in both groups was observed.Results There was no statistically significant difference in glycosylated hemoglobin(HbA1c),BMI,systolic blood pressure,diastolic blood pressure,total cholesterol,and low-density lipoprotein between young and elderly patients with type 2 diabetes(P>0.05).There was also no statistically significant difference in CVD risk factors including hypertension,obesity,hyperglycemia and hypercholesteremia(P>0.05).Furthermore,there were no statistically significant differences of cumulative proportion in zero CVD risk factor,one risk factor,two risk factors,three risk factors,and four risk factors in young and elderly patients with type 2 diabetes(P>0.05).There were no statistically significant differences in CVD cases at the end of follow-up time,CVD cases of follow up for five years,two CVD cases,and two or more CVD cases between the two groups(P>0.05).Conclusion The risk of CVD in young patients with type 2 diabetes is not lower than that in elderly patients.
作者
苑丛茹
董双华
皇甫晓燕
Yuan Congru;Dong Shuanghua;Huangfu Xiaoyan(Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050,China)
出处
《心脑血管病防治》
2020年第4期352-355,共4页
CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
关键词
心血管疾病
青年2型糖尿病
横断面研究
Cardiovascular disease
Young patients with type 2 diabetes
Cross-sectional study
作者简介
通讯作者:皇甫晓燕,Email :dui502532@163.com。
