摘要
目的分析双源CT灌注成像(CTP)联合CT血管造影(CTA)成像在进展性缺血性脑卒中诊断中的应用价值。方法选取2015年3月至2016年3月收治的44例进展性缺血性脑卒中患者,患者行CT平扫后进行脑CTP和CTA成像检查,观察CT灌注数据及动脉狭窄情况,脑CT灌注成像分析患者局部脑血流量(CBF)、脑血容量(CBV)和平均通过时间(MTT)等参数,分析两种检查方法的诊断效果,并分析两种检查方法对脑组织异常灌注、动脉狭窄的一致性。结果CTP检查发现38例异常灌注区与临床症状一致,灌注异常区CBV、CBF较镜像区明显降低(P<0.05);MTT较镜像区明显延长(P<0.05)。CTA检查发现34例存在责任血管,CTA发现责任血管狭窄且CTP灌注异常32例(72.72%),CTA未发现责任血管狭窄但CTP灌注异常6例(13.64%),CTA发现责任血管狭窄但CTP灌注正常2例(4.55%),CTA未发现责任血管狭窄且CTP灌注正常4例(9.09%);2组间差异有统计学意义(P<0.05)。结论CTP联合CTA成像能准确反映进展性缺血性脑卒中患者脑组织血流动力学变化,能够精确诊断疾病,为临床诊断提供更多有价值的信息并对个体化治疗提供更科学的参考依据。
Objective To investigate the diagnostic value of dual source CT perfusion imaging(CTP)combined with CT angiography(CTA)in patients with progressive ischemic stroke,so as to provide a scientific basis for clinical treatment.Methods A total of 44 patients with progressive ischemic verebral stroke,who were admitted and treated in our hospital from March 2015 to March 2016,were examined by CT perfusion imaging and CT angiography,then who underwent CT perfusion and CTA imaging examination.The CBF,CBV,MTT were analyzed according to the examination results,and the diagnostic efficiency and the consistency of the two methods in detecting abnormal brain perfusion,arterial stenosis and diagnostic results were analyzed.Results CTP examination showed that abnormal perfusion area was consistent with clinical symptoms in 38 cases,with abnormal perfusion of cerebral blood volume(CBV)and cerebral blood flow(CBF)being significantly decreased,as compared with those in mirror image area(P<0.05),and the mean transit time(MTT)was significantly prolonged(P<0.05).CTA examination found that 34 patients had responsible vascular condition,and 32 patients(72.72%)had responsible vascular condition and CTP perfusion abnormalities.Moreover CTA showed 6 patients(13.64%)had CTP perfusion abnormalities,without responsible vascular abnormalities,and 2 patients(4.55%)had responsible vascular stenosis and normal CTP perfusion.CTA found 4 patients(9.09%)had no CTP perfusion abnormalities and no responsible vascular abnormalities,The differences between the two groups were statistically significant(P<0.05).Conclusion CTP combined with CTA can accurately reflect the hemodynamic changes of cerebral tissue in patients with progressive ischemic stroke,and provide more valuable information and more scientific reference for clinical diagnosis.
作者
孟令雷
陈欣
尚新芳
高凤霄
李永才
MENG Linglei;CHEN Xin;SHANG Xinfang(Department of CT/MR,Xingtai People’s Hospital,Hebei,Xingtai 054001,China)
出处
《河北医药》
CAS
2020年第17期2626-2629,共4页
Hebei Medical Journal
基金
邢台市科学技术研究与发展支撑计划项目(编号:2018ZC191)。
