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A型肉毒毒素注射治疗面肌痉挛的方法改良 被引量:3

Improvement of botulinum toxin type A injection in the treatment of hemifacial spasm
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摘要 目的 A型肉毒毒素治疗面肌痉挛的两种不同注射方法所致口角歪斜发生率的差别。方法 2018年12月至2019年8月在阜阳市人民医院就诊的64例面肌痉挛病人,按随机数字表法分为A组、B组,A组32例采用传统单侧加健侧笑肌注射,B组32例在A组注射基础上添加健侧提口角肌群注射,分析A、B两组治疗后口角歪斜并发症的差异。结果两组总有效率均为100%,疗效差异无统计学意义(P>0.05),出现口角歪斜的占比分别为:A组9例(28.1%),B组1例(3.1%),B组明显低于A组(P<0.05)。结论面肌痉挛病人改良单侧联合健侧笑肌及提口角肌群注射A型肉毒毒素较传统单侧加健侧笑肌注射出现口角歪斜概率降低。 Objective To study the differences in the incidence of skewness caused by two different injection methods of botulinum toxin type A in the treatment of hemifacial spasm.Methods Sixty⁃four patients wity hemifacial spasm who were treated in Fuyang People’s Hospital were selected from December 2018 to August 2019.According to the random number table method,they were di⁃vided into the group A and group B.Thirty⁃two cases in the group A were given the traditional unilateral injection with the contralat⁃eral risorius injections,and 32 cases in the group B were given the musculus levator anguli orista group on the basis of injection in the group A.The differences in complication of distortion of commissure after treatment between the group A and B were analyzed.Results The total effective rate of both groups was 100%.The difference in curative effect between the two groups was not statisti⁃cally significant(P>0.05).The proportions of distortion of commissure of mouth were:9 cases in the group A(28.1%),1 case in the group B(3.1%),and the group B was obviously lower than the group A(P<0.05).Conclusion Compared with the traditional unilateral with contralateral risorius,the probability of distortion of commissure of the modified unilateral with contralateral risorius and musculus levator anguli orista group injection of botulinum toxin type A is lower for patients with hemifacial spasm.
作者 张建才 翟明锋 饶峰 秦亚勤 徐婷婷 李宗友 ZHANG Jiancai;ZHAI Mingfeng;RAO Feng;QIN Yaqin;XU Tingting;LI Zongyou(Department of Neurology,Fuyang People’s Hospital,Fuyang,Anhui 236000,China)
出处 《安徽医药》 CAS 2020年第9期1868-1870,共3页 Anhui Medical and Pharmaceutical Journal
关键词 面部单侧痉挛 A型肉毒毒素 面部肌肉 注射 肌肉内 口角歪斜 Hemifacial spasm Botulinum toxin type A Facial muscles Injections,intramuscular Distortion of commissure
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