摘要
目的探讨孕激素治疗无排卵型月经不调的应用效果。方法便利抽取该院2018年6月—2019年6月间接收的无排卵型月经不调患者184例,随机将其分为小剂量组(服用孕激素药物100 mg/d)与大剂量组(服用孕激素药物300 mg/d),每组均为92例,治疗结束对两组患者的治疗效果进行比较。结果两组患者的子宫内膜厚度、月经量、月经持续时间分别为(6.34±0.27)、(6.41±0.23)mm和(87.44±6.48)、(86.57±7.11)mL以及(5.54±1.48)、(5.57±1.11)d,均差异无统计学意义(t=1.893、0.867、0.156,P=0.060、0.387、0.877>0.05),小剂量组服药后不良反应率为7.61%(7/92),低于大剂量组患者36.96%(34/92),差异有统计学意义(χ^2=22.878,P=0.000<0.05)。结论在对无排卵型月经不调患者进行治疗和调理期间,采用小剂量的孕激素药物的治疗效果与大剂量孕激素药物治疗效果相差较小,但不良反应较轻。
Objective To explore the effect of progesterone on anovulatory irregular menstruation.Methods Convenient selection of 184 patients with anovulatory irregular menstruation received in the hospital from June 2018 to June 2019 were randomly divided into a low-dose group(taking progesterone drug 100 mg/d)and a high-dose group(progesterone drug 300 mg/d),92 cases in each group,and compare the treatment effect of the two groups at the end of treatment.Results The endometrial thickness,menstrual volume and menstrual duration of the two groups were(6.34±0.27),(6.41±0.23)mm and(87.44±6.48),(86.57±7.11)mL and(5.54±1.48),(5.57±1.11)d,the differences were not statistically significant(t=1.893,0.867,0.156,P=0.060,0.387,0.877>0.05),the adverse reaction rate after taking the small dose group 7.61%(7/92),lower than 36.96%(34/92)of patients in the high-dose group,the difference was statistically significant(χ^2=22.878,P=0.000<0.05).Conclusion During the treatment and conditioning of patients with anovulatory irregular menstruation,the therapeutic effect of using low-dose progestin drugs is smaller than that of high-dose progestin drugs,but the adverse reactions are mild.
作者
李翠菊
LI Cui-ju(Department of Obstetrics,Dongming County People's Hospital,Heze,Shandong Province,274500 China)
出处
《中外医疗》
2020年第18期38-40,共3页
China & Foreign Medical Treatment
关键词
不同剂量孕激素
无排卵型月经不调
宫内膜厚度
月经量
月经持续时间
不良反应率
Different doses of progesterone
Anovulatory irregular menstruation
Endometrial thickness
Menstrual volume
Menstrual duration
Adverse reaction rate
作者简介
李翠菊(1972-),女,山东菏泽人,本科,主治医师,研究方向:妇产科。
