摘要
Objective:To observe the clinical effect of auricular point sticking therapy for cardiac syndrome X(CSX)in women.Methods:A total of 64 patients were randomized into two groups by the random number table,with 32 cases in each group.Patients in the control group received conventional treatment for angina,while patients in the treatment group received auricular point sticking therapy on the basis of conventional treatment.After 8 weeks of treatment,the levels of serum estradiol(E2),nitric oxide(NO)and endothelium-1(ET-1)were compared to evaluate the therapeutic effect.Results:After 8 weeks of treatment,the total effective rate and markedly effective rate in the treatment group were significantly higher than those in the control group,and the between-group comparisons showed statistical significance(both P<0.05).After treatment,the scores of chest pain and tightness in the control group dropped significantly,and the intra-group comparisons showed statistical significance(both P<0.05);the scores of chest pain and tightness,palpitations,weakness and shortness of breath in the treatment group dropped significantly,and the intra-group comparisons showed statistical significance(all P<0.05);there were significant inter-group differences in the scores of chest pain and tightness.After treatment,the intra-group comparisons of E2,NO and ET-1 contents in the control group showed no statistical significance(all P>0.05),while the E2,NO and ET-1 contents in the treatment group changed significantly after treatment and were significantly different from those in the control group(all P<0.05).Conclusion:Auricular point sticking on the basis of conventional treatment was effective for CSX in women,and is worth clinical application.
目的:观察耳穴贴压对女性心脏X综合征(CSX)的临床疗效.方法:将64例患者采用随机数字表法分为2组,每组32例.对照组接受心绞痛常规治疗;治疗组在对照组治疗基础上加用耳穴贴压治疗.治疗8周后比较两组临床疗效及血清学雌二醇(E2)、一氧化氮(NO)和血管收缩肽内皮素-1(ET-1)的变化.结果:治疗8周后,治疗组的总有效率和显效率明显高于对照组,组间差异均有统计学意义(均P<0.05).治疗后,对照组胸痛和胸闷评分下降,与本组治疗前均有统计学差异(均P<0.05);治疗组胸痛、胸闷、心悸、乏力及气短评分均下降,与本组治疗前均有统计学差异(均P<0.05),胸痛和胸闷评分与对照组差异有统计学意义(均P<0.05).治疗后,对照组E2、NO及ET-1含量与治疗前差异均无统计学意义(均P>0.05);治疗组E2、NO及ET-1与本组治疗前及对照组治疗后差异均有统计学意义(均P<0.05).结论:常规药物治疗基础上加耳穴贴压治疗女性CSX疗效确切,值得临床推广.
作者
Zhang Ya-mei
Wang Jun
张亚梅;王俊(Xiaoshan Hospital of Zhejiang Province,Hangzhou 310013,China;Hangzhou Red Cross Hospital,Hangzhou 310003,China)
基金
浙江省杭州市红十字会医院院内科研基金,No.hhyn201702.
作者简介
张亚梅,M.M.,attending physician;Corresponding Author:王俊,M.D.,attending physician of traditional Chinese medicine.E-mail:8320791@qq.com。
