摘要
Oleanolic acid(OA)and its derivatives are widely found in diverse plants and are naturally effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles in various diseases such as ulcerative colitis,multiple sclerosis,metabolic disorders,diabetes,hepatitis and different cancers.This review assembles and presents the latest in vivo reports on the impacts of OA and OA derivatives from various plant sources and the biological mechanisms of OA activities.Thus,this review presents sufficient data proposing that OA and its derivatives are potential alternative and complementary therapies for the treatment and management of several diseases.
作者简介
Corresponding author:Alaattin Sen,PhD,Academic Fellow,Academic Research,Chairman,Full Professor,Instructor,Research Scientist,Senior Lecturer,Senior Researcher,Senior Scientist,Department of Molecular Biology and Genetics,Faculty of Life and Natural Sciences,Abdullah Gul University,Sumer Campus,Kocasinan,Kayseri 38080,Turkey.sena@agu.edu.tr。
