摘要
目的探索倍他乐克联合前列地尔治疗冠心病心绞痛患者的效果及对血流动力学的影响。方法选取2016年6月至2019年6月本院收治的冠心病心绞痛患者76例作为研究对象,根据治疗方法分为对照组和观察组,各38例。对照组应用常规治疗和倍他乐克(酒石酸美托洛尔)治疗,观察组在此基础上应用前列地尔注射液治疗,对比两组总有效率以及血流动力学指标。结果治疗10 d后,观察组总有效率为94.74%,高于对照组的76.32%,比较差异有统计学意义(P<0.05);治疗前两组患者的血流动力学指标对比差异无统计学意义;治疗10 d后观察组患者的纤维蛋白原水平、红细胞沉降率、全血黏度均低于对照组(P<0.001)。结论倍他乐克联合前列地尔治疗冠心病心绞痛疗效确切,有助于减低患者血液黏稠度,改善心肌供血,促进心绞痛症状缓解,值得临床推广。
Objective To explore the effect of betaloc combined with alprostadil in the treatment of coronary heart disease angina pectoris and its effect on hemodynamics.Methods 76 patients with coronary heart disease and angina pectoris were selected in our hospital from June 2016 to June 2019.They were divided into the control group and the observation group according to the treatment methods,with 38 cases in each group.The control group was treated with conventional treatment and betaloc(metoprolol tartrate),while the observation group was treated with alprostadil injection on this basis.The total effective rate and hemodynamic parameters of the two groups were compared.Results After 10 days of treatment,the total effective rate of the observation group was 94.74%higher than the control group of 76.32%(P<0.05).There was no significant difference in hemodynamic indexes between the two groups before treatment.After 10 days of treatment,the ibrinogen level,erythrocyte sedimentation rate and whole blood viscosity in the observation group were lower than those in the control group(P<0.001).Conclusion Betaloc combined with alprostadil in the treatment of coronary heart disease angina pectoris has an effective effect,which is helpful to reduce blood viscosity,improve myocardial blood supply and relieve angina pectoris symptoms.
作者
邱德和
Qiu Dehe(The Second Department of Internal Medicine,People's Hospital,Linchuan District,Fuzhou City,Jiangxi Province,Fuzhou,Jiangxi,344100,China)
出处
《当代医学》
2020年第16期42-44,共3页
Contemporary Medicine
关键词
倍他乐克
前列地尔
冠心病心绞痛
血流动力学
血液黏稠度
Betaloc
Alprostadil
Coronary heart disease angina pectoris
Hemodynamics
Blood viscosity
