摘要
Background Since the outbreak of C0VID-19,no data have been available for hospitalised psychiatric patients who are suspected to have COVID-19.We performed a comprehensive investigation of the clinical features of hospitalised patients with schizophrenia with or without suspected COVID-19 in Hubei Province,China.Aim To explore the clinical characteristics of hospitalised patients with schizophrenia with suspected COVID-19 in Hubei Province,China.M ethods 21 hospitalised patients with schizophrenia with suspected COVID-19(COVID-19 suspected group)in the isolation ward of a mental health hospital in Wuhan and 30 hospitalised patients with schizophrenia(clean group)in the general ward of another mental health hospital in Yichang were recruited.We retrospectively reviewed their clinical characteristics,laboratory findings and chest CT results before 21 February 2020.We also compared the emotional and mental symptoms between the two groups.Results Medical records revealed that 21 COVID-19 suspected patients were transferred to the isolation ward between 30 January 2020 and 15 February 2020.The mean age(SD)of COVID-19 suspected patients was 43.1(2.6).12(57.1%)patients showed abnormalities on chest CT before onset of respiratory symptoms.14(66.7%)patients had psychiatric medications adjustment after detection of abnormal chest CT findings.By 21 February,one patient was confirmed to have COVID-19.Even though the remaining 20(95.2%)were negative for at least two reverse transcription PCR tests,11(52.4%)patients met the diagnostic criteria for clinically confirmed cases.Compared with patients in the clean group,patients in the suspected COVID-19 group showed significantly higher stress,depression and anxiety levels and poorer sleep quality.Conclusion Setting up an independent isolation ward for hospitalised psychiatric patients who are suspected to have symptoms of COVID-19 helped control the spread of the epidemic.Patients with schizophrenia suspected to have COVID-19 showed increased stress and mood and sleep disturbances,which should be appropriately managed.
基金
This work was supported by the Program of Shanghai Academic Research Leader(17XD1403300)
the Shanghai Key Laboratory of Psychotic Disorders(13DZ2260500).
作者简介
Dr Xuebing Liu obtained a doctorate from Central South University Xiangya School of Medicine and now work as the director of addiction center of Wuhan mental health center.He is the member of Chinese Association of Drug Abuse Prevention and Treatment,Addiction Medicine Group of Chinese Society of Psychosomatic Medicine,and Committee of Dnig Dependence&Abuse of Chinese Society of Toxicology,and the secretary of Chinese Synthetic Drug Association of Chinese Association of Drug Abuse Prevention and Treatment.He also participates in many other national and local academic committees.His majar research interests include psychiatry and mechanisms,prevention and treatment of addiction;Dr Hong Lin,deputy director and psychotherapist.He obtained the master's degree from Wuhan University,and now he worked as the chief of Medical Department and Department of Medical Records in Yichang Special Care Hospital,and director of Teaching office of mental health center in China Three Gorges University.He was the member of Chinese Psychiatrist Association and Chinese Association of Drug Abuse Prevention and Treatment.He also participates in many other local academic committees.Besides,he takes in charge or participates in many national,provincial and municipal scientific research projects;Correspondence to Ruihua Li,E-mail:liruihua37@163.com;Correspondence to Dr Min Zhao,E-mail:drminzhao@gmail.com。
