摘要
肉芽肿性小叶性乳腺炎(GLM)是一种少见的乳腺良性疾病,近年来出现发病率上升的趋势。GLM是一种病因尚未明确的乳腺良性疾病,可能与自身免疫、高泌乳素血症、细菌感染等有关。GLM患者通常以乳房单侧外周肿块为主诉就诊,仅靠临床、影像及实验室检查常难以明确诊断。病理检查是GLM主要的诊断方法,组织病理学上,GLM表现为以乳腺终末导管小叶单位为中心的慢性化脓性肉芽肿性炎。因临床及病理医师对GLM认识不足,许多患者常被误诊为急性乳腺炎、乳腺结核、乳腺癌、浆细胞性乳腺炎等。因此,有必要对GLM的诊断及鉴别诊断进行深入讨论,以拓宽诊断思路。
Granulomatous lobular mastitis(GLM)is a rare benign breast disease and shows an increased incidence in recent years.The etiology of GLM is unknown,but various factors including autoimmunity,hyperprolactinemia and bacterial infection may be related to its occurrence.Patients with GLM usually complain of an unilateral peripheral breast mass.It is often difficult to make a definite diagnosis by clinical,imaging and laboratory examination alone.Pathological examination is the main diagnostic method.Histopathologically,GLM is characterized by chronic suppurative granulomatous inflammation centered on the lobular unit of the terminal duct of the breast.Many patients were misdiagnosed as acute mastitis,breast tuberculosis,breast cancer,plasma cell mastitis etc.due to a lack of cognition from the clinicians and pathologists.Therefore,it is necessary to discuss the diagnostic and differential diagnosis of GLM in depth in order to broaden the diagnostic thinking.
作者
刘启梁
雷美
LIU Qiliang;LEI Mei(Department of Pathology,Wuhan Pulmonary Hospital,Wuhan 430030,China)
出处
《医学综述》
2020年第10期1994-1998,共5页
Medical Recapitulate
关键词
肉芽肿性小叶性乳腺炎
鉴别诊断
病理
Granulomatous lobular mastitis
Differential diagnosis
Pathology
作者简介
通信作者:刘启梁,Email:lql880727@126.com。
