摘要
目的分析尿道狭窄临床治疗中输尿管镜联合球囊扩张导管的应用效果及影响。方法随机选取2008年3月~2019年3月于本院就诊尿道狭窄患者共88例纳为研究对象,开展临床回顾性研究。经确认手术治疗方案后,根据治疗术式的不同将其分为对照组42例、研究组46例。对照组接受冷刀切开治疗,研究组接受输尿管镜联合球囊扩张导管治疗。对比两组治疗前后临床指标数据变化及术后临床疗效、术后并发症情况。结果患者入院时,最大尿流率、国际前列腺症状评分及膀胱残余尿量组间对比结果差异无统计学意义(P>0.05);经治疗3个月后,两组最大尿流率、国际前列腺症状评分及膀胱残余尿量较入院时均有明显改善,但组间比较差异无统计学意义(P>0.05);经治疗12个月后,研究组最大尿流率、国际前列腺症状评分及膀胱残余尿量较对照组具有明显优势,差异有统计学意义(P<0.05);两组治疗效果差异无统计学意义(P>0.05);研究组手术时间、出血量、住院时间均明显优于对照组,差异有统计学意义(P<0.05);且两组术后均有个别病例合并术后并发症,比较差异无统计学意义(P>0.05)。结论尿道狭窄临床治疗中应用输尿管镜联合球囊扩张导管治疗术,可通过物理扩张形式实现对患者尿道狭窄段的有效扩张,实现对患者排尿症状的有效缓解,且安全性较高,但对于复杂性狭窄的治疗仍存在局限性,需在临床中结合患者实际合理应用。
Objective To analyze the application effect and influence of ureteroscope combined with balloon dilation catheter in the clinical treatment of urethral stricture.Methods 88 patients with urethral stricture treated at our hospital during the study period from March 2008 to March 2019 were randomly selected as the study objects for clinical retrospective study.After confirming the surgical therapeutic regimen,the patients were divided into the control group(42 patients)and the study group(46 patients)according to the different therapeutic methods.The control group received cold knife incision treatment,while the study group received the treatment of ureteroscope combined with balloon dilation catheter.The data changes in clinical indexes before and after treatment as well as postoperative clinical efficacy and postoperative complications were compared between the two groups.Results At admission of patients,there was no statistically significant difference in the inter-group comparison results of the maximum urine flow rate,international prostate symptom score,and residual urine volume in the bladder(P>0.05);After 3 months of treatment,the maximum urine flow rate,international prostate symptom score,and residual urine volume in the bladder in the two groups were significantly improved compared with those at admission,but the difference between the two groups was not statistically significant(P>0.05);After 12 months of treatment,the maximum urine flow rate,international prostate symptom score,and residual urine volume in the bladder in the study group had significant advantages over the control group,with statistically significant difference(P<0.05);There was no statistically significant difference in therapeutic effect between the two groups(P>0.05);The operation time,bleeding volume,and duration of hospitalization in the stady group were significantly better than those in the control group,with statistically significant difference(P<0.05);And there were individual cases with postoperative complications after surgery in the two groups,with no statistically significant difference(P>0.05).Conclusion Ureteroscope combined with balloon dilation catheter in the treatment of urethral stricture can achieve effective expansion of urethral stricture in patients through physical expansion,and achieve effective relief of patients’urination symptoms,with higher safety.However,there are still limitations in the treatment of complex stricture,and thus it shall be reasonably applied in clinical practice in combination with the actual situation of patients.
作者
谷亚明
韩阳军
左超
刁英智
GU Yaming;HAN Yangjun;ZUO Chao;DIAO Yingzhi(Department of Urinary Surgery,Miyun Teaching Hospital of Capital Medical University,Beijing 101500,China)
出处
《中国医药科学》
2020年第8期248-251,共4页
China Medicine And Pharmacy
关键词
输尿管镜
球囊扩张导管
尿道狭窄
国际前列腺症状评分
膀胱残余尿量
Ureteroscope
Balloon dilation catheter
Urethral stricture
International prostate symptom score
Residual urine volume in the bladder
