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二甲硅油散不同时间给药在结肠镜检查术前肠道准备中的效果观察 被引量:7

The Effect of Dimethacrylate Administered at Different Times on Intestinal Preparation before Colonoscopy
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摘要 目的:探讨二甲硅油散不同时间给药在结肠镜检查术前肠道准备中的效果,从而为患者选择更有效的肠道准备方法。方法:选取2019年1-3月拟行结肠镜检查的300例患者,随机分为A、B、C组,每组100例,分别于检查前1晚19:30-21:00第一杯、检查当日4:30-6:00第一杯、第三杯加入二甲硅油散2.5 g,比较三组肠道清洁、肠道气泡量及不良反应发生情况。结果:三组间肠道清洁有效率比较,C组>A组>B组,但差异均无统计学意义(P>0.05);C组肠道气泡优良率明显高于A组及B组(P<0.05),视野清晰;各组腹痛、腹胀和恶心、呕吐发生率比较,差异无统计学意义(P>0.05)。结论:二甲硅油散加入检查当日第三杯聚乙二醇(PEG)内服用,可明显减少肠道气泡,提高视野清晰度,降低不良反应发生率,更加适合患者进行术前肠道准备。 Objective:To investigate the effect of Dimethacrylate administered at different times on intestinal preparation before colonoscopy,so as to select more effective intestinal preparation methods for patients.Method:A total of 300 patients who were scheduled to undergo colonoscopy from January to March 2019 were randomly divided into group A,B,and C,with 100 patients in each group.Oral Dimethacrylate 2.5 g was taken respectively in 1st cup at 19:30-21:00 of the night before the examination and in 1st cup and 3rd cup at 4:30-6:00 on the day of the inspection.The cleanness and defoaming condition and adverse reactions were compared.Result:The efficiency of bowel cleanness was compared between the three groups,group C> group A > group B,but the difference was not statistically significant (P>0.05).The excellent rate of defoaming condition in group C was significantly higher than that of group A and group B (P<0.05),the visual field was clear.There was no significant difference in the incidence of abdominal pain,bloating and nausea and vomiting in each group (P>0.05).Conclusion:Dimethacrylate added to the third cup of PEG on the day of the inspection can obviously reduce the intestinal bubbles,improve the visibility of the visual field,reduce the incidence of adverse reactions,and is more suitable for patients with preoperative bowel preparation.
作者 郭卫波 罗治文 王璇 何万里 张丽丽 GUO Weibo;LUO Zhiwen;WANG Xuan;HE Wanli;ZHANG Lili(Beijing Beiya Orthopedic Hospital,Beijing 100245,China)
出处 《中外医学研究》 2020年第11期139-141,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 结肠镜检查 肠道准备 二甲硅油散 复方聚乙二醇 Colonoscopy Intestinal preparation Dimethacrylate Polyethylene Glycol
作者简介 通信作者:罗治文。
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