摘要
目的探讨序贯疗法治疗胃溃疡幽门螺杆菌(Hp)阳性患者的临床效果及安全性。方法选取本院2018年6月至2019年6月收治的104例胃溃疡Hp阳性患者,按照抽签法分为对照组(52例,采用标准四联疗法治疗)和研究组(52例,采用序贯疗法治疗)。比较两组疗效及安全性。结果研究组治疗总有效率(98.08%)高于对照组(82.69%),差异有统计学意义(P<0.05);研究组Hp根除率(98.08%)高于对照组(80.77%),差异有统计学意义(P<0.05);研究组不良反应发生率(3.85%)低于对照组(17.31%),差异有统计学意义(P<0.05)。结论胃溃疡Hp阳性患者采用序贯疗法治疗效果更显著,且不良反应少,值得临床推广。
Objective To explore the clinical efficacy and safety of sequential therapy in patients with gastric ulcer positive helicobacter pylori(Hp).Methods 104 patients with positive gastric ulcer and Hp were selected from June 2018 to June 2019 in our hospital. They were divide into the control group(52 cases, was treated with standard quadruple therapy) and the study group(52 cases, was treated with sequential therapy) by random sampling method. The efficacy and safety of the two groups were compared. Results The total effective rate of treatment in the study group(98.08%) was higher than that in the control group(82.69%), and the difference was statistically significant(P<0.05). The eradication rate of Hp in the study group(98.08%)was higher than that in the control group(80.77%), and the difference was statistically significant(P<0.05). The incidence of adverse reactions in the study group(3.85%) was lower than that in the control group(17.31%), and the difference was statistically significant(P<0.05). Conclusion Sequential therapy is more effective in patients with gastric ulcer with positive Hp and less adverse reactions, which is worthy of clinical promotion.
作者
彭文斌
Peng Wenbin(The First Affiliated Hospital of Shaoyang College,Changsha,Hunan,422000,China)
出处
《当代医学》
2020年第14期28-29,共2页
Contemporary Medicine
关键词
胃溃疡
HP阳性
序贯疗法
临床效果
安全性
Gastric ulcer
Hp positive
Sequential therapy
Clinical effect
Security
