摘要
近年来,幽门螺杆菌的高感染率及其对心血管疾病的影响引发了人们的关注,其可能通过炎症反应、免疫反应和损伤内皮细胞等多种机制直接参与冠心病、脑卒中等心血管疾病的发生发展,同时也可在动脉粥样硬化、高血压、高同型半胱氨酸血症和血脂异常等心血管疾病危险因素的形成中发挥重要作用。但目前国内外研究结果尚不一致,仍需要通过大量实验进一步确证,以采取有效措施控制心血管疾病的发生率。本文现就幽门螺杆菌与心血管疾病的流行情况、国内外研究现状及其相互作用机制进行综述。
In recent years,the high infection rate of Helicobacter pylori and its impact on cardiovascular disease have attracted public attention.It may directly affect coronary heart disease,stroke,etc.through various mechanisms such as inflammation,immune response,and damage to endothelial cells.It could also play an important role in the formation of cardiovascular disease risk factors such as atherosclerosis,hypertension,hyperhomocysteinemia,and dyslipidemia.However,domestic and international research results are still inconsistent,and a large number of experiments are still required to confirm it to take effective measures to control the incidence of cardiovascular disease.This article reviews the prevalence of Helicobacter pylori and cardiovascular disease,the interaction mechanisms and the status of relevant domestic and international researches.
作者
唐碧玮
王学梅
吴静
Tang Biwei;Wang Xuemei;Wu Jing(School of Public Health,Inner Mongolia Medical University,Hohhot 010110,China;National Center for Chronic and Noncommunicable Disease Control and Prevention,Chinese Center for Diseases Control and Prevention,Beijing 100050,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2020年第3期327-331,共5页
Chinese Journal of Preventive Medicine
基金
国家重点基础研究发展计划(2016YFC1302600)。
关键词
螺杆菌
幽门
心血管疾病
动脉粥样硬化
Helicobacter pylori
Cardiovascular diseases
Atherosclerosis
作者简介
通信作者:吴静,Email:wujing@chinacdc.cn。
