摘要
目的探讨脑梗塞患者部分生化指标与代谢综合征的相关性。方法收集本院神经内科的住院患者120例为脑梗塞组(入院后诊断为代谢综合征);对照组为本院进健康体检者,共计211例。对空腹研究对象采集肘部静脉血,EDTA抗凝,抽血后立即送检,使用西门子生化分析仪分析。结果脑梗塞组空腹血糖、C-反应蛋白、总胆固醇、血甘油三酯、血低密度脂蛋白胆固醇、血高密度脂蛋白胆固醇、尿酸明显增高,分别为[(7. 6±0. 3) mmol/L,(12. 6±2. 8) mmol/L,(6. 2±1. 1) mmol/L,(2. 1±0. 6) mmol/L,(1. 2±0. 4) mmol/L,(2. 9±0. 8) mmol/L,(653. 4±132. 5)μmol/L],差异均有统计学意义(P <0. 05)。将单因素分析中P <0. 05的变量纳入Logistic回归分析,Logistic多因素回归分析显示空腹血糖、脂代谢、尿酸、C-反应蛋白与脑梗死相关。结论血脂代谢、尿酸、C-反应蛋白为脑梗塞伴代谢综合征患者增加的独立危险因素,脑梗塞伴代谢综合征患者应该及早对以上危险因素进行干预。
Objective To investigate the correlation between cerebral infarction and biochemical index in patients with metabolic syndrome. Methods A total of 120 inpatients from the Department of Neurology of our hospital were collected as the cerebral infarction group( diagnosed as metabolic syndrome after admission);the control group was a total of 211 normal people who came to our hospital for a physical examination. Venous blood was taken from fasting subjects for EDTA anticoagulation,and the blood was submitted and tested immediately for analysis by Siemens biochemical analyzer. Results It was found that compared with the control group,fasting blood glucose,lipid metabolism,uric acid,C-reactive protein of the cerebral infarction group significantly increased( 7. 6 mmol/L ± 0. 3 mmol/L,12. 6 mmol/L ± 2. 8 mmol/L,6. 2 mmol/L ± 1. 1 mmol/L,2. 1 mmol/L ±0. 6 mmol/L,1. 2 mmol/L ± 0. 4 mmol/L,2. 9 mmol/L ± 0. 8 mmol/L,653. 4 mmol/L ± 132. 5 μmol/L),and the differences were statistically significant( P < 0. 05). The variables with P < 0. 05 in univariate analysis were included in Logistic regression analysis. Logistic multivariate regression analysis showed that fasting blood glucose, lipid metabolism, uric acid, and C-reactive protein were related to cerebral infarction. Conclusion Lipid metabolism,uric acid,and C-reactive protein are independent risk factors for patients with cerebral infarction and metabolic syndrome. And the above items should be intervened as soon as possible in patients with cerebral infarction and metabolic syndrome.
作者
郭平安
洪亚明
马银丽
GUO Ping-an;HONG Ya-ming;MA Yin-li(Clinical Laboratory,the First People's Hospital of Fuyang District,Hangzhou,Zhejiang 311400,China)
出处
《中国卫生检验杂志》
CAS
2020年第4期466-468,共3页
Chinese Journal of Health Laboratory Technology
关键词
脑梗塞
代谢综合征
生化指标
相关性
Cerebral infarction
Metabolic syndrome
Biochemical index
Correlation
作者简介
郭平安(1980-),男,本科,主管技师,主要从事检验科生化检验工作。
