摘要
近年来我国炎症性肠病(IBD)的发病率不断上升,随着糖皮质激素、免疫抑制剂和生物制剂等的应用,大多数IBD患者的病情得到控制,但也增加了机会感染的风险。其中巨细胞病毒(CMV)感染是IBD患者常见的机会感染,可能导致病情进展加快、治疗效果欠佳、增加手术风险和死亡率。早期诊断,必要时早期治疗,是控制疾病发展及改善预后的关键。本文就IBD合并CMV感染的流行病学、临床表现、结肠镜检查、实验室检查及治疗的研究进展做一综述。
In recent years,the incidence of inflammatory bowel disease(IBD)has continued to increase in China.With the application of glucocorticoids,immunosuppressants and biological agents,the condition of most patients with IBD has been controlled,however the risk of opportunistic infection has also increased.Among them,cytomegalovirus(CMV)infection is a common opportunistic infection in patients with IBD,which may lead to accelerated disease progression,poor treatment results,increased surgical risk and mortality.Early diagnosis and necessary early treatment are the keys to controlling disease development and improving prognosis.This article reviews the research progress of epidemiology,clinical manifestations,colonoscopy,laboratory tests and treatment of IBD combined with CMV infection.
作者
黄丽
唐清
Huang Li;Tang Qing(Department of Pediatrics,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)
出处
《广西医科大学学报》
CAS
2020年第2期320-325,共6页
Journal of Guangxi Medical University
关键词
炎症性肠病
巨细胞病毒
流行病学调查
inflammatory bowel disease
cytomegalovirus
epidemiological investigation
作者简介
通信作者:唐清。
