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2014—2018年某院鲍曼不动杆菌临床分布及耐药分析

Analysis on the clinical distribution and drug resistance of acinetobacter baumannii in a hospital from 2014 to 2018
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摘要 目的分析本院鲍曼不动杆菌的临床分布及耐药情况,为临床合理使用抗生素提供依据。方法回顾性分析本院2014年1月至2018年12月住院患者各类标本,利用仪器法进行鉴定及药敏试验,对鲍曼不动杆菌的分布特征及耐药情况进行分析。结果分离出鲍曼不动杆菌408株,主要来源于痰标本,占64.7%。科室分布由高到低排列依次为ICU、呼吸内科、肿瘤科、神经外科及综合科。抗生素中仅有多粘菌素B耐药率低于50.0%(耐药率为0.3%),其余的耐药率均高于50.0%。结论本院鲍曼不动杆菌耐药情况较严重,医院应积极开展其耐药性检测,制定合理的抗生素用药方案,加强手卫生、环境物表管理,以防止多重耐药菌的扩散。 Objective To analyze the clinical distribution and drug resistance of acinetobacter baumannii in our hospital to provide basis for the proper use of antibiotics in clinic.Methods Various specimens from inpatients in our hospital from January 2014 to December 2018 were retrospectively analyzed.Identification and drug sensitivity test were implemented by the instrument method,analysis on the clinical distribution and drug resistance of acinetobacter baumannii.Results 408 strains of acinetobacter baumannii were isolated,mainly from sputum specimens(64.7%).The main distribution was ICU,respiratory department,oncology department,neurosurgery department,and general department.Only the drug resistance rate of polymyxin B was less than 50.0%in antibiotics(0.3%),and that of the rest were all more than 50.0%.Conclusion The drug resistance of acinetobacter baumannii in our hospital is very serious.The hospital should actively carry out its drug resistance test,develop a reasonable usage program of antibiotic drugs,strengthen hand hygiene,environmental and object surface management,in order to prevent the spread of multi drug resistant bacteria.
作者 黄锐航 韩福郎 Huang Ruihang;Han Fulang(Nanhai People's Hospital,Foshan 528200,China)
出处 《国际医药卫生导报》 2020年第5期719-721,共3页 International Medicine and Health Guidance News
关键词 鲍曼不动杆菌 耐药性 抗生素 合理用药 Acinetobacter baumannii Drug resistance Antibiotic Rational administration of drug
作者简介 通信作者:韩福郎,Email:20269105@qq.com。
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  • 1周颖杰,李光辉.成人及儿童复杂性腹腔内感染的诊断与处理:美国外科感染学会及美国感染病学会指南[J].中国感染与化疗杂志,2010,10(4):241-247. 被引量:248
  • 2李苏利,李杨,华川.多重耐药鲍氏不动杆菌耐药现状与临床对策[J].中华医院感染学杂志,2005,15(12):1438-1440. 被引量:103
  • 3王辉,孙宏莉,宁永忠,杨启文,陈民钧,朱元珏,徐英春,谢秀丽.不动杆菌属多重耐药及泛耐药的分子机制研究[J].中华医学杂志,2006,86(1):17-22. 被引量:183
  • 4Tsai HT, Wang JT, Chen C J, et al. Association between antibiotic us- age and subsequent colonization or infection of extensive drug resistant Acinetobacter baumannii : a matched case control study in intensive care units[J]. Diagn Microbiol Infect Dis,2008,62(3):298-305.
  • 5Fernandez Cuenca F, Martinea - Martinea L, Conejo MC, et at. Rela -tionship between beta lactamase production, outermembrane pro- tein and penicillin binding protein profiles on the activity of carbapene- msagainst clinical isolates of Acinetobacter baumannii [J ]. J Antimlcrob Chem Other, 2003, 51 ( 3 ) : 565.
  • 6Seigel J D,Rhinehart E,Jackson M.Chiarello L.Healthcare Infection Control Practices Advisory Committee.Guideline for isolation precautions:preventing transmission of infectious agents in healthcare settings[EB/OL].(2007-07).http://www.cdc.gov/ncidod/dhqp/pdf/isolation 2007.
  • 7Saeed S,Fakih M G,Reiderer K,et al.Interinstitutional and intrainstitutional transmission of a strain of Acinetobacter baumannii detected by molecular analysis:comparison of pulsedfield gel electrophoresis and repetitive sequence-based polymerase chain reaction[J].Infect Control Hosp Epidemiol,2006,27(9):081-993.
  • 8Silvia Munoz-Price L,Weinstein R A.Acinetobacter infection[J].N Engl J Med,2008,358(26):1271-1281.
  • 9Fournier P E,Vallenet D,Barbe V,et al.Comparative genomics of multidrug resistance in Acinetobacter baumannii[J].PLoS Genet,2006,2(1)e7:0062-0072.
  • 10Ling M L,Ang A,Wee M,et al.A nosocomial outbreak of multiresistant Acinetobacter baumannii originating from an intensive care unit[J].Infect Control Hosp Epidemiol,2001,22(1):48-49.

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