摘要
目的:探讨磁共振血管造影(magnetic resonance angiography,MRA)中侧支循环与脑卒中预后的关系。方法:选择2017-05-01~2018-10-31在本院就诊的急性脑卒中患者55例,均于治疗前、治疗后24 h内接受MRI及MRA检查。根据改良Rankin量表(modified Rankin scale,mRS)评估3个月后的预后情况,mRS 0~2分为预后良好组,mRS 3~6分为预后不良组。统计分析两组侧裂及软脑膜侧支循环的差异。结果:55例患者中侧裂侧支循环不丰富者52例,软脑膜侧支循环不丰富者45例。侧裂和软脑膜侧支循环不丰富的患者中,预后良好组的年龄、入院NIHSS评分、术前梗死体积均低于预后不良组(P<0.05)。多元Logistic回归分析显示,年龄、软脑膜的侧支循环是预测脑卒中预后的独立因子。预后良好组的梗死体积小于预后不良组,然而多元Logistic回归分析显示术后梗死体积对预测脑卒中预后无显著意义。结论:软脑膜的侧支循环可预测脑卒中预后,而术后梗死体积与脑卒中预后的关系仍需进一步研究。
Objective:To evaluate the relationship between the collateral circulation on magnetic resonance angiography(MRA)and stroke prognosis.Methods:Fifty-five acute stroke patients from 2017-05-11 to 2018-10-31 were selected.All patients underwent MRI and MRA examination before therapy and after therapy within 24 h.Conditions of prognosis at 3 months was assessed by using the modified Rankin scale(mRS).mRS was 0-2 as good prognosis group and 3-6 was poor prognosis group.Statistical methods were used to analyze the collateral circulation differences in lateral fissure and pia mater between the two groups.Results:Cases with insufficient collateral circulation at the lateral fissure was 52 and pia mater was 45.The age,NIHSS score at arrival and preoperative infarct volume in good prognosis group were significantly lower than those in poor prognosis group(P<0.05).Multivariate Logistic showed that age and collateral circulation at the pia mater were independent factors for prediction of stroke.The infarct volume in good prognosis group was smaller than that in poor prognosis group,while multivariate Logistic showed that postoperative infarct volume was non-significant in predicting the clinical outcome after stroke.Conclusion:The extent of collateral circulation at the pia mater may be useful for predicting the prognosis after stoke.While the relationship between postoperative infarct volume and clinical outcome still requires for further study.
作者
陈广浩
邱建博
郑少青
马跃虎
CHEN Guanghao;QIU Jianbo;ZHENG Shaoqing;MA Yuehu(Department of Radiology,Nanjing Hospital Affiliated to Nanjing Medical University,Nanjing First Hospital,Nanjing 210006,China)
出处
《西北国防医学杂志》
CAS
2020年第2期93-98,共6页
Medical Journal of National Defending Forces in Northwest China
基金
江苏省社会发展面上项目(BE2017614)~~
关键词
急性脑卒中
侧支循环
血管再通治疗
磁共振血管造影
acute ischemic stroke
collateral circulation
endovascular recanalization
magnetic resonance angiography
作者简介
陈广浩(1991-),男,E-mail:327712855@qq.com;通讯作者:马跃虎(1976-),男,硕士,副主任医师,E-mail:mayuehu1976@163.com。
