期刊文献+

牙周翻瓣术联合应用盐酸米诺环素治疗慢性牙周炎的临床效果 被引量:5

Clinical Observation of Curative Effects of Periodontal Flap Surgery Combined with Minocycline Hydrochloride in the Treatment of Chronic Periodontitis
在线阅读 下载PDF
导出
摘要 目的:研究牙周翻瓣术联合盐酸米诺环素治疗慢性牙周炎的效果。方法:选取2015年9月1日-2018年9月1日在笔者所在医院治疗的慢性牙周炎患者108例,采用随机方法将其分为两组,每组54例。对照组采用牙周翻瓣术进行治疗,观察组在对照组的基础上应用盐酸米诺环素治疗。比较两组治疗前及治疗后6周及6个月的临床牙周指数,包括临床附着丧失(clinical attachment loss,CAL)、龈沟出血指数(sulcus bleeding index,SBI)及探诊深度(probing depth,PD)。结果:治疗后6周及6个月两组患者各项临床牙周指数均较治疗前明显降低(P<0.05)。观察组治疗后6周及6个月SBI及PD均显著低于对照组,差异有统计学意义(P<0.05),但两组治疗后6周及6个月CAL比较差异均无统计学意义(P>0.05)。结论:在慢性牙周炎治疗中,采用牙周翻瓣术联合盐酸米诺环素的改善效果优于单一牙周翻瓣术,有利于临床治疗。 Objective:To investigate the curative effects of periodontal flap surgery combined with Minocycline Hydrochloride in the treatment of chronic periodontitis.Method:A total of 108 patients with chronic periodontitis who were treated in our hospital from September 1 st,2015 to September 1 st,2018 were selected and randomly divided into two groups,with 54 case in each group.The control group was treated with periodontal flap surgery,and the observation group was treated with Minocycline Hydrochloride on the basis of the control group.The clinical periodontal index,including clinical attachment loss(CAL),sulcus bleeding index(SBI)and probing depth(PD)were compared between the two groups before and 6 weeks and 6 months after treatment.Result:After 6 weeks and 6 months of treatment,the clinical periodontal index of the two groups were significantly lower than those before treatment(P<0.05).The SBI and PD of the observation group were significantly lower than those of the control group at 6 weeks and 6 months after treatment,the differences were statistically significant(P<0.05),but there were no significant differences in CAL between the two groups at 6 weeks and 6 months after treatment(P>0.05).Conclusion:In the treatment of chronic periodontitis,the improvement effect of periodontal flap surgery combined with Minocycline Hydrochloride is better than that of single periodontal flap surgery and is conducive to clinical treatment.
作者 何柳静 HE Liujing(Xingning People’s Hospital,Xingning 514500,China)
机构地区 兴宁市人民医院
出处 《中外医学研究》 2020年第5期31-33,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 牙周翻瓣术 盐酸米诺环素 慢性牙周炎 Periodontal flap surgery Minocycline Hydrochloride Chronic periodontitis
  • 相关文献

参考文献13

二级参考文献72

  • 1葛少华,杨丕山,赵宁.米诺环素作为牙周手术根面处理剂的临床研究[J].牙体牙髓牙周病学杂志,2005,15(5):279-282. 被引量:6
  • 2郭瑞章.牙周翻瓣术治疗重症牙周病87例临床评估[J].中国科技信息,2005(10):141-141. 被引量:1
  • 3王岩,李凤元,曾红燕.牙周翻瓣术联合盐酸米诺环素治疗慢性牙周炎的疗效[J].首都医科大学学报,2006,27(3):306-309. 被引量:10
  • 4Shelburne CE, Prabhu A, Gleason RM, et al. Quantitation of Bacteroides forsythus in subgingival plaque comparison of immunoassay and quantitative polymerase chain reaction [J]. J Microbiol Methods, 2000,39(2) : 97 -107.
  • 5Lyons SR, Griffen AL, Leys EJ. Quantitative real-time PCR for Porphymonas gingivalis and total bacteria[ J]. J Clin Mi- crobiol, 2000, 38 (6) : 2362 - 2365.
  • 6Eguchi T, Koshy G, Umeda M, et al. Microbial changes in patients with acute periodontal abscess after treatment detec- ted by Pado Test[J]. Oral Dis, 2008,14(2) :180 -184.
  • 7Nonnenmaeher C, Dalpke A, Rochon J, et al. Real-time polymerase chain reaction for detection and quantification of bacteria in periodontal patients [ J ]. J Periodontol, 2005, 76 (9) : 1542 -1549.
  • 8王延春.慢性牙周炎的治疗原则[J].中外健康文摘,2009,6(34):246-247.
  • 9罗建美.观察盐酸米诺环素缓释剂治疗老年牙周炎84例的临床疗效[J].健康大视野,2013,21(14):143-144.
  • 10Rajalingham S, Das S. Antagonizing IL- 6 in ankylosing spon- dylitis: a short review [ J 1. Inflamm Allergy Drug Targets, 2012, 11 (4): 262-265.

共引文献283

同被引文献49

引证文献5

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部