摘要
目的探讨夜发性额叶癫痫的临床特征和诊断。方法报告2例夜发性额叶癫痫病例,并复习相关文献,总结其病因、发病机制、临床特点及诊治经验。结果本文2例病人以罕见的夜发性窒息感为先兆,出现过度运动和自动症,并继发全面性发作。神经影像和动态脑电图检查未见明显异常,易误诊为异态睡眠、假性发作等。经长程视频脑电图监测明确诊断。抗癫痫药治疗效果好。结论夜发性额叶癫痫发作形式多样,长程视频脑电图监测是确诊本病的关键。
Objective To investigate the clinical features and diagnosis of nocturnal frontal lobe epilepsy(NFLE).Methods Two cases of NFLE were reported and a literature review was performed to summarize the etiology,pathogenesis,clinical features,and diagnosis/treatment of this disease.Results Both patients had rarely seen nocturnal asphyxia as the premonitory symptom and then experienced excessive movement and automatism,followed by generalized seizure.Neuroimaging and dynamic electroencephalography showed no marked abnormality,and the patients were easily misdiagnosed with parasomnia and pseudoepileptic seizures.Long-term video-electroencephalography was performed to make a confirmed diagnosis.Antiepileptic drugs had a good therapeutic effect.Conclusion NFLE has various types of seizures,and long-term video-electroencephalography is the key to a confirmed diagnosis of this disease.
作者
于辛
蔡金晓
钟春娟
YU Xin;CAI Jinxiao;ZHONG Chunjuan(Department of Neurology,Chinese People’s Liberation Army No.971 Hospital,Qingdao 266071,China)
出处
《青岛大学学报（医学版）》
CAS
2020年第1期116-118,共3页
Journal of Qingdao University(Medical Sciences)
基金
青岛市医药科研指导计划项目(2015-WJZD134)
关键词
癫痫
额叶
夜间性突发性张力障碍
脑电描记术
病例报告
epilepsy
frontal lobe
nocturnal paroxysmal dystonia
electroencephalography
case reports
作者简介
第一作者:于辛(1971-),女,博士,副主任医师。E-mail:132-10255909@163.com。
