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丁丙诺啡透皮贴剂对多发肋骨骨折患者炎性因子和氧化应激指标水平的影响观察 被引量:2

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摘要 目的观察丁丙诺啡透皮贴剂对多发肋骨骨折患者炎性因子和氧化应激指标水平的影响。方法将84例多发肋骨骨折患者分为两组(n=42),A组接受静脉自控镇痛,B组加用丁丙诺啡透皮贴剂。使用VAS量表评估两组患者入院时和治疗7d时的疼痛程度;对比两组患者入院时和治疗7d时的IL-6、IL-8等炎性因子水平和MDA、SOD等氧化应激指标水平。结果B组治疗7d时的VAS评分低于A组(P<0.05);B组治疗7d时的IL-5、IL-8水平均低于A组(P<0.05);B组治疗7d时的SOD水平高于A组,而MDA水平较低(P<0.05)。结论丁丙诺啡透皮贴剂可有效缓解多发肋骨骨折患者疼痛程度,且能抑制机体炎症和氧化应激反应。
出处 《首都食品与医药》 2020年第2期60-60,共1页 Capital Food Medicine
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