摘要
目的:观察疏肝调神针刺联合逍遥散治疗围绝经期肝气郁结型失眠的临床疗效。方法:将90例围绝经期肝气郁结型失眠患者随机分为西药组、中药组和针药结合组,每组各30例。西药组口服艾司唑仑片治疗,中药组口服逍遥散治疗,针药结合组在中药组基础上给予疏肝调神针刺治疗。三组均治疗21 do治疗前后,观察各组患者匹兹堡睡眠质量指数(PSQI)评分,评价各组疗效。治疗结束6个月后,比较各组复发率。结果:治疗后,中药组和针药结合组PSQI各项评分较治疗前均降低(PV0.05),西药组仅入睡时间、睡眠时间、睡眠效率评分较治疗前降低(PV0.05);针药结合组和中药组睡眠质量、睡眠障碍、日间功能障碍评分均低于西药组(PV0.05);针药结合组PSQI各项评分均低于中药组(PV0.05)。西药组总有效率86%,中药组总有效率60%,针药结合组总有效率83%,西药组和针药结合组总有效率均高于中药组(PV0.05),西药组与针药结合组总有效率相当(P>0.05)。治疗结束6个月后,西药组复发率高于中药组与针药结合组,差异有统计学意义(PV0.05),针药结合组与中药组复发率比较,差异无统计学意义(P>0.05)。结论:疏肝调神针刺联合逍遥散治疗围绝经期肝气郁结型失眠临床疗效与艾司唑仑片相当,且疏肝调神针刺联合逍遥散改善睡眠质量、睡眠障碍、日间功能障碍和降低复发率的效果优于艾司唑仑片。
Objective:To observe the clinical curative efficacy of Shugan Tiaoshen(疏肝调神)acupuncture therapy combined with Xiaoyao Powder(逍遥散)in treating perimenopausal insomnia of liver qi stagnation type.Methods:A total of 90 patients with perimenopasual insomnia of live qi stagnation type were randomized into western medicine group,Chinese medicine group and acupuncture combined with medicine group,with 30 cases in each group.Patients in the western medicine group was treated with oral administration of estazolam tablet,those in the Chinese medicine group was treated with oral administration of Xiaoyao Powder,and in the acupuncture combined with medicine group,the patients were treated with Shugan Tiaoshen acupuncture therapy on the basis of the Chinese medicine group.All the three groups were treated for 21 days.After treatment,the scores of Pittsburgh sleep quality index(PSQI)scale and the curative efficacy of all the groups were compared.Six months after the end of treatment,the recurrence rate of all the groups were compared.Results:After treatment,all the scores of PSQI of the Chinese medicine group and the acupuncture combined with medicine group were lower than those before treatment(P<0.05),while in the western medicine group,only the scores of time to fall asleep,sleep time and sleep efficiency were lower than those before treatmen(P<0.05).The scores of sleep quality,sleep disorder and daytime dysfunction of the acupuncture combined with medicine group and the Chinese medicine group were lower than those of the western medicine group(P<0.05).All the scores of PSQI of the acupuncture combined with medicine group were lower than those of the Chinese medicine group(P<0.05).The total effective rate of the western medicine group,the Chinese medicine group and the acupuncture combined with medicine group was 86%,60%and 83%,respectively.The total effective rate of the western medicine group and the acupuncture combined with medicine group was higher than that of the Chinese medicine group(P<0.05).The total effective rate of the western medicine group and the acupuncture combined with medicine group was almost the same(P>0.05).Six months after the end of treatment,the recurrence rate of the western medicine group was higher than that of the Chinese medicine group and the acupuncture combined with medicine group(P<0.05).The difference of recurrence rate between the acupuncture combined with medicine group and the Chinese medicine group was not statistically significant(P>0.05).Conclusions:In treating perimenopausal insomnia of liver qi stagnation type,Shugan Tiaoshen acupuncture therapy combined with Xiaoyao Powder is as effective as estazolam tablet,and its efficacy on improving sleep quality,sleep disorder,daytime dysfunction and reducing recurrence rate is better than that of estazolam tablet.
作者
曹朝霞
黄志强
谢宇平
CAO Zhaoxia;HUANG Zhiqiang;XIE Yuping(Department of Acupuncture and Moxibustion,Dazhou Hospital of Integrative Traditional Chinese and Western Medicine,Dazhou 635000,China;Department of Neurology,Dazhou Hospital of Integrative Traditional Chinese and Western Medicine,Dazhou 635000,China;Sleep Medical Center,Gansu Provincial People's Hospital,Lanzhou 730000,China)
出处
《山东中医杂志》
2020年第2期145-148,共4页
Shandong Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(编号:81560228)
关键词
疏肝调神
针刺
逍遥散
围绝经期失眠
肝气郁结
匹兹堡睡眠质量指数
Shugan Tiaoshen
acupuncture
Xiaoyao Powder
perimenopausal insomnia
liver qi stagnation
Pittsburgh Sleep Quality Index
作者简介
曹朝霞(1990-),女,四川绵阳人,医学硕士,住院医师,主要从事针灸治疗失眠的临床研究;通信作者:谢宇平(1964-),男,主任医师,硕士研究生导师,主要从事睡眠诊治研究。邮箱:xyp5894@163.com。
