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负荷剂量替格瑞洛联合阿司匹林对急性心肌梗死患者PCI治疗效果的影响 被引量:6

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摘要 目的探究负荷剂量替格瑞洛联合阿司匹林对急性心肌梗死患者经皮冠状动脉介入(PCI)治疗效果的影响。方法回顾性分析110例急性心肌梗死行PCI术后患者的临床资料,按治疗方法不同分为对照组(氯吡格雷组)和观察组(负荷剂量替格瑞洛组)。比较两组心肌梗死溶栓试验(TIMI)分级、心肌灌注(TMPG)分级,炎症介质水平及心肌酶谱指标变化情况。结果PCI术后观察组TIMI、TMPG分级水平均高于对照组(P<0.01),IL-6、CRP、TNF-α、LDH、CK-MB、CTnI水平均低于对照组(P<0.01)。结论负荷剂量替格瑞洛联合阿司匹林治疗可改善急性心肌梗死患者PCI术后心肌血流灌注,有效减轻机体炎症反应及心肌损伤程度,有利于促进患者康复。
出处 《白求恩医学杂志》 2019年第5期475-477,共3页 Journal of Bethune Medical Science
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