摘要
目的探讨FibroScan瞬时弹性成像测定肝脏和脾脏硬度值预测肝硬化相关EVB的价值。方法选取75例乙肝肝硬化患者,根据患者的食管静脉曲张程度可以将其划分为重度、中度、轻度以及无静脉曲张,根据患者的出血情况可以划分为多次出血、单次出血和无出血,根据患者的Child-Pugh分级划分为A、B、C三级,所有患者均使用FibroScan瞬时弹性成像测定肝脏和脾脏硬度值,比较各个不同分组患者的肝脾硬度值差异。结果在不同Child-Pugh分级患者中,A级和B级患者的肝脏硬度值均显著低于C级患者(t=20.837,t=12.394,P<0.05);B级和C级患者的脾脏硬度值均显著高于A级患者(t=11.092,t=9.837,P<0.05)。随着静脉曲张程度的升高,患者的肝脾硬度值也随之升高,差异具有统计学意义(F=7.485,F=8.384,均P<0.05);重度和中度、轻度静脉曲张患者的肝硬度值均显著高于无静脉曲张组患者(t=27.343,t=15.493,t=10.726,均P<0.05);重度和中度、轻度静脉曲张患者的脾硬度值均显著高于无静脉曲张组患者(t=18.633,t=12.029,t=8.873,均P<0.05)。多次出血和单次出血患者的肝硬度值显著高于无出血组患者(t=18.847,t=13.293,均P<0.05);多次出血和单次出血患者的脾硬度值均显著高于无出血组患者(t=17.283,t=12.122,均P<0.05)。结论在预测乙肝肝硬化患者出现破裂出血方面,使用FibroScan瞬时弹性成像测定肝脏和脾脏硬度值具有较高的参考价值。
Objective The value of FibroScan instantaneous elastic imaging in predicting liver and spleen hardness in predicting EVB associated with liver cirrhosis was analyzed.Methods Between September 2018 and June 2019,75 hepatitis B patients with liver cirrhosis were chosen.Those patients were divided into heavy,medium,light and free of varicose veins depending on the degree of esophageal varices;divided into single,multiple and no hemorrhage according to patients'bleeding status;and divided into level A,B,C 3 according to the patient's Child-Pugh grades.FibroScan instantaneous elastic imaging measurement was used to measure the liver and spleen hardness value in all patients and differences of liver and spleen hardness value of all patients in different groups were compared.Results In patients with different child-pugh grades,liver hardness values of grade A and B patients were significantly lower than those of grade C patients(t=20.837,t=12.394,P<0.05).The spleen hardness values of grade B and C patients were significantly higher than those of grade A patients(t=11.092,t=9.837,P<0.05).With the increase of varicose veins,the hardness of liver and spleen of patients also increased,and the difference was statistically significant(F=7.485,F=8.384,all P<0.05).Liver hardness values in patients with severe,moderate and mild varicose veins were significantly higher than those in patients without varicose veins(t=27.343,t=15.493,t=10.726,all P<0.05).The spleen hardness value of patients with severe,moderate and mild varicose veins was significantly higher than that of patients without varicose veins(t=18.633,t=12.029,t=8.873,all P<0.05).Liver hardness values of patients with multiple bleeding and single bleeding were significantly higher than those of patients without bleeding(t=18.847,t=13.293,all P<0.05).The spleen hardness value of patients with multiple bleeding and single bleeding was significantly higher than that of patients without bleeding(t=17.283,t=12.122,all P<0.05).Conclusion In predicting ruptured bleeding in patients with hepatitis B liver cirrhosis,FibroScan instantaneous elastic imaging has a high reference value for measuring the hardness of liver and spleen.This technique is non-invasive,simple and repeatable,which is worth popularizing and applying in clinic.
作者
王妍
金仲群
马晓玲
WANG Yan;JIN Zhongqun;MA Xiaoling(Department of Ultrasound,Shijiazhuang First Hospital,Shijiazhuang 050000,P.R.China;Functional Department of Hebei Hospital of Traditional Chinese Medicine,Shijiazhuang 050011,P.R.China;Department of Critical Care Medicine,Shijiazhuang First Hospital,Shijiazhuang 050000,P.R.China)
出处
《医学影像学杂志》
2019年第12期2059-2062,共4页
Journal of Medical Imaging
关键词
乙型肝炎
肝硬化
瞬时弹性成像技术
硬度值
Hepatitis B
Liver cirrhosis
Transient elastic imaging
Hardness value
作者简介
王妍(1989-),女,河北衡水人,毕业于华北理工大学,本科学历,主治医师,主要从事医学影像学诊断工作;通信作者:金仲群,主任医师,E-mail:735185272@qq.com。
