摘要
目的:探讨细胞形态学(包括细胞化学染色)在初诊急性白血病中的诊断价值,以提高细胞形态学的重视程度。方法:回顾性分析我院2016年4月-2018年6月确诊的119例急性白血病患者临床资料,按形态学分型、免疫学分型,分别比较与最终诊断的诊断符合率。结果:单纯形态学分型的诊断符合率为76.5%,单纯免疫学分型的诊断符合率为79.8%,2者对急性白血病的诊断符合率比较,差异无统计学意义。结论:细胞形态学是诊断急性白血病的基石,在急性白血病的诊断中具有与免疫学分型相似的价值,应得予足够的重视;MICM综合诊断,可提高最终诊断率,对急性白血病患者的治疗和预后有一定的指导意义。
Objective:To investigate the diagnostic value of cytomorphology(including cytochemical staining)in newly diagnosed acute leukemia,so as to improve the importance of cytomorphology.Methods:The clinical data of 119 cases of acute leukemia diagnosed in our hospital from April 2016 to June 2018 were analyzed retrospectively.According to morphologic and immunological typing,accordance rate to final diagnosis was compared.Results:The diagnostic accordance rate of simple morphological typing was 76.5%,and the diagnostic accordance rate of simple immunological typing was 79.8%,the difference of diagnostic coincidence rate was not significant between the two groups of acute leukemia.Conclusion:Cytomorphology is the cornerstone of the diagnosis of acute leukemia,it has similar value to immunological classification in the diagnosis of leukemia and should pay enough attention.MICM comprehensive diagnosis can improve the final diagnosis rate,showing a guidance significance for the treatment and prognosis of patients with acute leukemia.
作者
林萍
谢若腾
张雅兰
张学亚
LIN Ping;XIE Ruo-Teng;ZHANG Ya-Lan;ZHANG Xue-Ya(Department of Laboratoryial Medicine,The Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,Fujian Province,China;Department of Hematology,The Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,Fujian Province,China)
出处
《中国实验血液学杂志》
CAS
CSCD
北大核心
2019年第6期1806-1811,共6页
Journal of Experimental Hematology
关键词
细胞形态学
免疫分型
急性白血病
诊断
cytomorphology
immunophenotyping
acute leukemia
diagnosis
作者简介
通信作者:张学亚,副主任医师.E-mail:jakey3456@sina.com。
