摘要
基因组选择(GS)是近些年发展起来的一项新型育种技术,目前已在动植物育种实践中应用。本研究通过在1068头杜洛克公猪群体中使用不同密度的SNP芯片进行全基因组选择效果比较分析。结果发现:使用基因型填充后芯片以及高密度SNP芯片所获得的估计基因组育种值(GEBV)之间可以达到99%的相关,并发现个体间亲缘关系的远近对同群体内基因型填充结果的准确率影响不大。由此可见,与目标性状紧密相关的低密度SNP芯片可用于实际育种工作,在降低使用成本的同时并不影响全基因组选择效果,为实质性进行猪分子育种提供了一条可行途径。
Genomic selection(GS)is a breeding technique developed in recent years,which now has been applied in animals and plants breeding field.In this study,the GS effects were compared among a male Duroc population consisting of 1068 individuals by using different density SNP chips.The obtained results indicated that genomic estimated breeding values(GEBV)correlation is around 99%between high-density SNP chip group and genotype-imputed chips group.And we also found that the kinship between individuals had little effect on the accuracy of genotype imputing in this population.In summary,the low-density SNP chip closely related to target traits could be used for future pig breeding,which can not only reduce the cost without affecting selection effect,but also provide a feasible way for pig molecular breeding.
作者
王珏
刘成琨
刘德武
王克君
陈洁
吴珍芳
方美英
WANG Jue;LIU Chengkun;LIU Dewu;WANG Kejun;CHEN Jie;WU Zhenfang;FANG Meiying(College of Animal Science and Technology,China Agricultural University,Beijing 100086,China;Berry Genomics Corporation,Beijing 102200,China;College of Animal Science,South China Agricultural University,Guangdong Guangzhou 510642,China;College of Animal Science and Veterinary Medicine,Henan Agricultural University,Henan Zhengzhou 450002,China)
出处
《中国畜牧杂志》
CAS
北大核心
2019年第12期75-79,共5页
Chinese Journal of Animal Science
基金
国家科技重大专项(2018ZX08009-28B)
作者简介
王珏(1991-),男,新疆乌鲁木齐人,博士研究生,研究方向为动物遗传育种与繁殖,E-mail:juewang@cau.edu.cn;通讯作者:方美英(1971-),女,E-mail:meiying@cau.edu.cn。
