摘要
目的探讨高海拔贫困地区动脉粥样硬化(AS)患者血尿酸水平与饮食习惯的相关性,为高海拔贫困地区AS患者的健康宣教提供理论依据。方法随机选取2017年1月至2019年1月成都市第三人民医院心内科收治的150例AS患者为研究对象,统计AS患者血尿酸水平及高尿酸血症(HUA)发生率,按照AS患者是否存在HUA分为HUA组(n=45)和非HUA(n=105)组,比较两组患者一般资料、饮食习惯(以高盐、高脂肪、高碳水化合物等膳食因素为例),分析AS患者发生HUA的影响因素;采用Pearson参数分析AS患者血尿酸水平与膳食因素的关系。结果AS患者平均血尿酸水平为(396.35±45.28)μmol/L;HUA患者发生率为30.00%(45/150);HUA组血尿酸水平明显高于非HUA组(P<0.05);HUA组患者年龄≥60岁比例、每日脂肪摄入量明显高于非HUA组,差异有统计学意义(P<0.05);两组其他因素比较,差异无统计学意义(P>0.05);Logistic回归分析显示,年龄、每日脂肪摄入量是AS患者发生HUA的影响因素(P<0.05);相关性分析表明,AS患者血尿酸水平与每日脂肪摄入量呈明显正相关(r=0.327,P<0.05)。结论年龄、饮食习惯(膳食因素)是高海拔贫困地区AS患者HUA发生的影响因素,通过加强对高龄患者健康宣教及严格的饮食指导,有利于高海拔贫困地区AS患者病情控制和预后改善。
Objective To explore the correlation between the blood uric acid(BUA)level and dietary habits of patients with atherosclerosis(AS)in high altitude poverty areas so as to provide a theoretical basis for the health education of AS patients in those areas.Methods A total of 150 AS patients admitted to Chengdu Third People’s Hospital from January of 2017 to January of 2019 were randomly selected as the subjects.The BUA levels and the incidence of hyperuricemia(HUA)in those subjects were statistically analyzed.The AS patients were divided into the HUA group and non-HUA group according to whether those patients had HUA or not.The general data and dietary habits(such as the dietary factors including high salt,high fat and high carbohydrate)were compared between the two groups.The influencing factors of HUA in AS patients were analyzed.The Pearson parameters were used to analyze the relationship between the BUA level and dietary factors in AS patients.Results The mean BUA level of the AS patients was(396.35±45.28)μmol/L and the incidence of HUA was 30.00%(45/150).The BUA level of the HUA group was significantly higher than that of the non-HUA group(P<0.05).The proportion of the patients no less than 60 years old and the daily fat intake in the HUA group were significantly higher than those in the non-HUA group(P<0.05).There was no significant differences in the other factors between the two groups(P>0.05).The results of Logistic regression analysis indicated that age and daily fat intake were the influencing factors of HUA in AS patients(P<0.05).The results of correlation analysis showed that there was significantly positive correlation between the BUA level and daily fat intake(r=0.327,P<0.05).Conclusion Age and dietary habits(dietary factors)are the influencing factors of HUA in the AS patients of high altitude poverty areas.Strengthening the health education and strict dietary guidance for elderly patients is beneficial to the disease control and prognosis improvement of AS patients in high altitude poverty areas.
作者
刘红
王引利
郭良敏
李伟萍
庞芹
Liu Hong;Wang Yinli;Guo Liangmin;Li Weiping;Pang Qin(Department of Cardiology,Chengdu Third People's Hospital,Chengdu 610031,China)
出处
《成都医学院学报》
CAS
2019年第6期769-772,777,共5页
Journal of Chengdu Medical College
基金
四川省卫生计划生育委员会科研项目(No:18PJ383)
关键词
动脉粥样硬化
血尿酸
饮食习惯
相关性
Atherosclerosis
Blood uric acid
Dietary habit
Correlation