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临床病理技术在胸腔积液细胞块中的应用价值探讨 被引量:4

The Clinical Application Value of Clinicopathologic Technique in Pleural Effusion Cell Block
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摘要 目的分析临床病理技术在胸腔积液细胞块中的应用价值。方法该文研究对象为胸腔积液患者,研究总例数200例,收取时间在2018年2月-2019年2月之间,总例数采取抽签分组方式分为两组,观察组100例(实施临床病理技术)、对照组100例(实施传统涂片制片),两组胸腔积液患者均实施HE染色和免疫组化染色,分析患者的鉴别诊断结果和患者病理特性,对比两组的检出率、误诊率以及漏诊率、巨检、镜检结果。结果观察组患者检出率90.00%(其中阴性患者10例、所占比为10.00%;阳性患者90例、所占比90.00%)高于对照组患者,差异有统计学意义(χ~2=4.619;P<0.05);观察组患者的误诊率5.00%、漏诊率5.00%低于对照组患者,差异有统计学意义(χ~2=10.286、5.556;P<0.05);巨检:通过对胸腔积液患者进行巨检后,其中20例胸腔积液患者包膜呈现完整,患者其余样本和自身邻近组织无显著界限,患者对应切面是灰褐色或者灰白色。镜检:通过对胸腔积液患者样本进行镜检,患者样本具有黏膜特点,细胞壁和人体正常淋巴细胞相比,其较大、并且细胞核容易被深染,主要表现是颗粒状。结论临床病理技术在胸腔积液细胞块中具有显著的应用价值,而临床病理技术显著优于传统涂片制片,具有较高检出率,能够预防误诊和漏诊情况的发生,值得研究。 Objective To analyze the application value of clinicopathologic technique in pleural effusion cell block. Methods In this pa-per, the object of study for patients with pleural effusion, study of 200 cases, total charging time from February 2018 to February2019, 2019, between the total number of cases to the grouping of lottery is divided into two groups, observation group 100 cases(the implementation of clinical pathology technique), the control group, 100 cases(the implementation of traditional smear producer), two groups of patients with pleural effusion are the implementation of HE staining and immunohistochemical staining, analysis results and the differential diagnosis of patients with pathological characteristics of patients, compared two groups of detection rate, misdiagnosis rate, missed diagnosis and autopsy, microscopic examination results. Results The detection rate of the observation group was 90.00%(including 10 cases of negative patients, accounting for 10.00%;90 cases of positive patients, accounting for 90.00%) were higher than those of the control group(χ~2= 4.619;P<0.05);The misdiagnosis rate of the observation group was 5.00%, and the rate of missed diagnosis was 5.00% lower than that of the control group,the difference was statistically significant(χ~2=10.286, 5.556;P<0.05). Major examination: after the major examination of patients with pleural effusion, the capsule of 20 patients with pleural effusion presented complete, the rest of the samples of patients had no significant boundary with their adjacent tissues, and the corresponding section of patients was grayish brown or grayish white. Microscopic examination: the samples of patients with pleural effusion were examined under the microscope. The patient samples had mucosal characteristics. The cell walls were larger than normal lymphocytes, and the nuclei were more prone to hyperstaining. Conclusion Clinicopathologic technique has significant application value in pleural effusion cell mass, and clinicopathologic technique is significantly better than traditional smear preparation, with higher detection rate, and can prevent misdiagnosis and missed diagnosis, which is worthy of study.
作者 闵学文 MIN Xue-wen(Department of Pathology,Jurong City People's Hospital,Jurong,Jiangsu Province,212400 China)
出处 《世界复合医学》 2019年第11期124-126,132,共4页 World Journal of Complex Medicine
关键词 临床病理技术 胸腔积液细胞块 应用价值 探讨 Clinicopathology Pleural effusion cell mass Application value To discuss
作者简介 闵学文(1972-),男,江苏句容人,本科,主管技师,研究方向:病理学技术。
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