摘要
随着经济的快速发展、人民饮食结构的改变及环境污染,消化系统癌症的发病率及死亡率呈逐年上升趋势,对于早期癌症可行内镜下治疗,进展期可采用外科手术、放疗、化疗、免疫治疗及靶向治疗等方法。近年来,多项研究显示,他汀类药物在消化系统癌症中的使用可一定程度上降低癌症患者的死亡率及患癌风险。本文主要探讨他汀类药物在消化系统癌症中的应用研究进展,有望为癌症的治疗发现新的辅助用药。
With the rapid development of the economy,the change of people’s diet structure and environmental pollution,the incidence and mortality of cancer in the digestive system show an increasing trend. Surgery is the first choice in the early stage,and radiotherapy、chemotherapy、immunotherapy and targeted therapy can be adopted in the later stage. In recent years,several studies have shown that the use of statins in digestive cancer can reduce the mortality and cancer risk of cancer patients to some extent. This article mainly discusses that progress in the use of statins in cancers of the digestive system,which is expected to find new adjuvant drugs for the treatment of cancer.
作者
杨珍
虎金朋
牛敏
周燕
张玲
张雪
白飞虎
Yang Zhen;Hu Jinpeng;Niu Min;Zhou Yan;Zhang Ling;Zhang Xue;Bai Feihu(Ningxia Medical University,Ningxia 750004,China;Northwest Nationalities University First Clinical Medical College,Ningxia 750002,China;People′s Hospital of Ningxia,Ningxia 750002,China)
出处
《中华胃肠内镜电子杂志》
2019年第3期125-129,共5页
Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)
基金
国家自然科学基金项目(81760440)
中央引导地方科技发展专项(YDZX20176400004650)
宁夏消化疾病临床医学研究中心(2018CXPT0075)
关键词
他汀类药物
食管癌
胃癌
肝癌
胆管癌
胰腺癌
结直肠癌
Statins
Esophageal cancer
Gastric cancer
Liver cancer
Biliary tract cancer
Pancreatic cancer
Colorectal cancer
作者简介
通信作者:白飞虎,Email:baifeihu@sohu.com。
