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窄带成像放大内镜结合靛胭脂染色在筛查早期胃癌中的临床应用

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摘要 目的探讨窄带成像放大内镜结合靛胭脂染色在慢性胃炎伴糜烂患者筛查中发现早期胃癌的临床应用。方法通过自2016年1月-2017年6月间因嗳气、反酸、腹痛、腹胀等症状来我院消化门诊就诊,经过胃镜检查中发现慢性胃炎伴糜烂可疑病变患者1,736例。忽略年龄、性别、职业等因素,根据患者就诊数字分成两组,即观察组(ME-NBI+靛胭脂染色)及对照组(靛胭脂染色)。观察组白光进镜,发现糜烂灶(隆起、平坦、凹陷),行靛胭脂染色,对不染或淡染色病灶再行ME-NBI检查,根据ME-NBI诊断标准(与周围粘膜有明显界线;存在微血管或微形态异常的病灶)取组织病理检查;对照组采用常规内镜检查,白光进镜,发现病灶,用靛胭脂染色后,对不染色或淡染色病灶取组织病理检查。统计观察组与对照组发现早期胃癌、高级别上皮内瘤变、中度非典型增生病灶的数量及百分比,得出观察组与对照组间的差异性。结果窄带成像放大内镜结合靛胭脂染色比靛胭脂染色在慢性胃炎伴糜烂的患者中更好地发现早期胃癌及癌前病变(高级别瘤变、中度非典型增生)。二者之间有明显的差异性(P<0.05)。结论窄带成像放大内镜结合靛胭脂染色在慢性胃炎伴糜烂的患者中能很好地发现早期胃癌及癌前病变,值得在基层医院推广应用。
出处 《心电图杂志(电子版)》 2019年第4期96-98,共3页 Journal of Electrocardiogram(Electronic Edition)
基金 窄带成像放大内镜结合靛胭脂染色在早期胃癌中的临床应用(No.1504)
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