摘要
目的分析影响氨溴索联合布地奈德(BUN)治疗小儿肺炎临床疗效的因素以及防治策略。方法选取2016年12月至2018年12月在我院接受治疗的88例小儿肺炎患者作为研究对象,根据治疗的有效性将患者分为显著组与不佳组,其中显著组61例,不佳组27例,对比两组患者的年龄、体重、性别、是否进行氧疗、住院时间、病程、体内是否缺少微量元素、是否伴有慢性潜在病、雾化吸入方式以及治疗前最高温度与居住地等情况的差异,对可能影响氨溴索联合BUN治疗小儿肺炎临床疗效的因素进行多因素logistic回归分析。结果两组研究对象的年龄、是否进行氧疗、雾化吸入方式对比,差异具有统计学意义(χ^2值分别为4.737、5.587、5.791,均P<0.05)。多因素logistic回归分析发现年龄<4岁、没有进行氧疗、使用超声雾化的吸入方式均会影响小儿肺炎的治疗效果(OR值分别为3.728、4.577、5.013,均P<0.05)。结论年龄<4岁、没有进行氧疗、使用超声雾化的吸入方式是影响氨溴索联合BUN治疗小儿肺炎临床疗效的因素,对于低龄患儿应积极转移患儿对治疗的注意力,根据具体情况选择雾化吸入方式,若患儿出现缺氧现象应及时进行氧疗。
Objective To analyze the factors affecting the clinical efficacy of ambroxol combined with budesonide(BUN) in the treatment of pediatric pneumonia and the prevention and treatment strategies.Methods From December 2016 to December 2018,88 children with pneumonia who were treated in our hospital were selected as subjects.According to the effectiveness of the treatment,the patients were divided into significant group(n=61) and poor group(n=27).Comparing the differences between the two groups of patient’s the age,weight,sex,oxygen therapy,length of hospital stay,duration of disease,lack of trace elements in the body,chronic potential disease,aerosol inhalation,maximum temperature before treatment and place of residence.Multivariate logistic regression analysis was performed on factors that may affect the clinical efficacy of ambroxol combined with BUN in the treatment of children with pneumonia.Results There were significant differences in age,oxygen therapy and atomization inhalation between the two groups(χ^2 values were 4.737,5.587 and 5.791,respectively,all P<0.05).Multiple factors logistic regression analysis found that age <4 years,no oxygen therapy,and inhalation of ultrasonic atomization were the factors affecting the clinical efficacy of ambroxol combined with BUN in the treatment of children with pneumonia(OR values were 3.728,4.577 and 5.013,respectively,all P<0.05).Conclusion Age <4 years old,no oxygen therapy,and inhalation of ultrasonic atomization are the factors influencing the clinical efficacy of ambroxol combined with BUN in the treatment of children with pneumonia.Younger children should actively divert their attention to treatment and choose atomization inhalation method according to the specific situation.If children appear hypoxia phenomenon should be timely oxygen therapy.
作者
余楚烈
黄红宇
周琼
YU Chulie;HUANG Hongyu;ZHOU Qiong(Department of Internal Medicine,Hangzhou Childrens Hospital,Hangzhou 310000,Zhejiang,China;Department of Child Healthcare,Hangzhou Children's Hospital,Hangzhou 310000,Zhejiang,China)
出处
《中国妇幼健康研究》
2019年第10期1281-1284,共4页
Chinese Journal of Woman and Child Health Research
关键词
氨溴索
布地奈德
小儿肺炎
影响因素
防治策略
ambroxol
budesonide
pediatric pneumonia
influencing factors
prevention strategy
作者简介
余楚烈(1984-),男,主治医师,主要从事儿内科研究;通讯作者:黄红宇,副主任医师。
