摘要
目的:分析免疫球蛋白治疗对新生儿感染性肺炎临床表现、经皮血氧饱和度和IgG水平的影响。方法:选择86例感染性肺炎患儿作为研究对象,随机分为2组,各43例;对照组给予常规治疗,联合组给予常规治疗+免疫球蛋白联合治疗。比较2组患儿治疗后临床疗效、临床症状改善、经皮血氧饱和度和IgG水平等指标差异。结果:联合组治疗总有效率为95.35%,高于对照组的76.74%(P<0.05)。联合组患儿治疗后吸痰次数、咳嗽缓解时间、退热时间、气促消失时间、肺部湿啰音时间及住院时间较对照组均明显减少(P<0.01)。2组患儿治疗后经皮血氧饱和度和IgG水平较治疗前均升高,且联合组较对照组升高(P<0.01)。结论:在常规治疗的基础上,对新生儿感染性肺炎患儿给予免疫球蛋白治疗可有效改善临床症状,减少症状消失或改善的时间,亦可有效提高患儿免疫功能,取得良好的治疗效果。
Objective:To analyze the effects of immunoglobulin therapy on the clinical manifestation,percutaneous oxygen saturation and IgG level of neonates with infective pneumonia.Methods:A total of 86 neonates with infectious pneumonia were randomly divided into the control group and combined group(43 cases in each group).The control group and combined group were treated with the routine method and routine method combined with immunoglobulin.The clinical effect,clinical symptom improvement,percutaneous oxygen saturation and IgG level were compared between two groups.Results:The total effective rate in combined group(95.35%)was higher than that in control group(76.74%)(P<0.05).After treatment,the sputum suction times,cough relief time,pyretolysis time,disappearance time of shortness of breath,time of moist rale in lung and time of hospitalization in combined group significantly reduced compared with control group(P<0.01).After treatment,the percutaneous oxygen saturation and IgG level in two groups were significantly higher than those before treatment,and which in combined group was significantly higher than that in control group(P<0.01).Conclusions:On the basis of the routine treatment,the immunoglobulin therapy in neonatal infectious pneumonia can effectively improve the clinical symptoms,reduce the symptom disappearance or improvement time,improve the immune function,and has better effect.
作者
田丽
TIAN Li(Neonatal Intensive Care Unit,Heze Municiple Hospital,Shandong Heze274000,China)
出处
《蚌埠医学院学报》
CAS
2019年第10期1341-1343,1348,共4页
Journal of Bengbu Medical College
作者简介
田丽(1981-),女,主治医师.
