摘要
基于蜂针疗法对中风具有显著的治疗效果,而其活血化瘀的科学内涵尚未完全阐明;同时考虑血瘀是中风的中心环节,以及血清溶血磷脂酸(Lysophosphatidic Acid,LPA)、组织型纤溶酶原激活物(tissue Plasminogen Activator,tPA)和人纤溶酶原激活物抑制因子1(Plasminogen Activator Inhibitor-1,PAI-1)等在血瘀证的病理生理过程起到的重要作用,所以笔者通过文献的研究与分析,提出如下假设:蜂针疗法的活血化瘀作用可能与其抑制了LPA的表达,从而影响了通路的下游效应指标(tPA、PAI-1)的释放等有关。
Based on efficacy of bee acupuncture on cerebral infarction,its scientific connotation of Huoxue Huayu(活血化瘀)has not been fully elucidated.Because blood stasis is the central link of stroke,and LPA,tPA and PAI-1 were effective on the Xueyu syndrome(血瘀证),the author puts forward the following hypothesis:Huoxue Huayu from bee acupuncture may inhibit the expression of LPA,thus affecting the downstream effect index of the pathway(tPA,PAI-1)release.
出处
《中医临床研究》
2019年第20期14-16,共3页
Clinical Journal Of Chinese Medicine
作者简介
通讯作者:马晓睿。