摘要
随着老龄化社会的到来,骨质疏松症(osteoporosis,OP)已成为全球范围内严重危害人们健康的常见慢性疾病之一。中医药是我国独特的医疗卫生资源,在骨质疏松症防治方面具有一定的优势。动物模型是医学实验研究过程中的重要载体,采用病证结合动物模型研究疾病已成为中医药研究的重要内容,是中医药现代化研究中不可或缺的部分。本文旨在对目前常用的骨质疏松症动物模型和病证结合动物模型的构建及评价方法进行总结,以期为从事骨质疏松症实验研究的科研工作者提供参考。
With the advent of an aging society, osteoporosis has become one of the most common chronic diseases that seriously endanger people ’s health worldwide. Traditional Chinese medicine is a unique medical and health resource in China. It has certain advantage in the prevention and treatment of osteoporosis. Animal model is an important carrier in the process of medical experimental research. The use of disease syndrome combined with animal model to study disease has become an important part of traditional Chinese medicine research, and it is an indispensable part of modernization research of traditional Chinese medicine. This paper aims to summarize the current construction and evaluation method of osteoporosis model and disease syndrome combination model, in order to provide reference for researchers engaged in experimental research of osteoporosis.
作者
孙凯
魏戌
朱立国
戴建业
章轶立
谢雁鸣
SUN Kai;WEI Xu;ZHU Liguo;DAI Jianye;ZHANG Yili;XIE Yanming(Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China;Lanzhou University School of Pharmacy, Lanzhou 730020, China;Beijing University of Chinese Medicine, Beijing 100102, China;Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2019年第9期1340-1344,共5页
Chinese Journal of Osteoporosis
基金
国家自然科学基金青年基金项目(81704102)
中华中医药学会(2017-2019年度)青年人才托举工程项目(CACM-2017-QNRC2-A03)
中国中医科学院“十三五”重点领域科研项目(ZZ10-022)
关键词
骨质疏松症
病证结合
动物模型
造模方法
osteoporosis
integration of disease and syndrome
animal model
modeling method
作者简介
通信作者:魏戌,Email:weixu.007@163.com;通信作者:朱立国,Email:zhlg95@aliyun.com.
