摘要
目的对黄芪注射液联合硫酸镁和盐酸拉贝洛尔治疗改善妊娠高血压患者NO水平和细胞因子水平的效果进行探讨。方法于2017年6月-2018年5月便利选择该院收治的妊娠高血压患者100例,依据随机数字表法分为实验组和常规组,每组50例。常规组接受硫酸镁和盐酸拉贝洛尔治疗,实验组在此基础上接受黄芪注射液治疗,统计并对比两组治疗效果。结果实验组治疗总有效率96.0%,显著高于常规组的82.0%,组间差异有统计学意义(χ^2=5.012,P=0.025)。治疗前实验组IL-4、IFN-γ、NO与常规组对比差异无统计学意义(P>0.05)。治疗后实验组IL-4、NO分别为(41.8±10.3)ng/L、(15.6±3.7)mmol/L,显著高于常规组的(31.2±10.3)ng/L、(7.5±3.5)mmol/L。治疗后实验组IFN-γ为(257.7±54.5)ng/L,显著低于常规组的(335.8±52.3)ng/L(t=16.467,P=0.000;t=13.545,P=0.000;t=18.862;P=0.000)。结论黄芪注射液联合硫酸镁和盐酸拉贝洛尔治疗妊娠高血压能够使其细胞因子和NO水平得到有效改善,具有较高推广价值。
Objective From June 2017 to May 2018 to investigate the effect of Huangqi Injection convenient combined with magnesium sulfate and labetalol hydrochloride on the improvement of NO and cytokine levels in patients with pregnancyinduced hypertension. Methods 100 patients with pregnancy-induced hypertension were enrolled in our hospital. According to the random number table method, they were divided into experimental group and routine group, with 50 cases in each group. The conventional group received magnesium sulfate and labetalol hydrochloride. The experimental group received Huangqi injection on this basis, and the results of the two groups were compared and compared. Results The total effective rate of the experimental group was 96.0%, which was significantly higher than that of the conventional group(82.0%). The difference between the two groups was statistically significant(χ^2=5.012, P=0.025). There was no statistically significant difference in the IL-4, IFN-γ, NO between the experimental group and the conventional group before treatment(P>0.05). After treatment, the IL-4 and NO in the experimental group were(41.8±10.3) ng/L and(15.6±3.7) mmol/L, respectively, which was significantly higher than that of the conventional group(31.2±10.3) ng/L,(7.5±3.5) mmol/L. After treatment, the IFN-γof the experimental group was(257.7±54.5) ng/L, which was significantly lower than that of the conventional group(335.8±52.3) ng/L(t=16.467, P=0.000;t=13.545, P=0.000;t=18.862;P=0.000). Conclusion Astragalus injection combined with magnesium sulfate and labetalol hydrochloride can effectively improve cytokine and NO levels in patients with pregnancyinduced hypertension, which has a high promotion value.
作者
王春红
WANG Chun-hong(Department of Obstetrics and Gynecology, People's Hospital of Fangzi District, Weifang, Shandong Province, 261000 China)
出处
《中外医疗》
2019年第21期98-99,114,共3页
China & Foreign Medical Treatment
关键词
妊娠高血压
黄芪注射液
盐酸拉贝洛尔
Pregnancy-induced hypertension
Astragalus injection
Labetalol hydrochloride
作者简介
王春红(1970-),女,山东潍坊人,本科,主治医师,研究方向:妇产科。
