摘要
目的探究CT诊断肺磨玻璃结节的应用价值。方法对石家庄市第一医院2015年6月至2019年6月施行胸部CT筛查发现磨玻璃结节的256例患者进行调查,分析其中241例肺磨玻璃结节患者CT扫描的影像学资料,对比134例浸润性腺癌(IAC)、76例微浸润腺癌(MIA)、31例浸润前病变患者的病灶大小、体积、实性成分及CT征象。结果IAC、MIA、浸润前病变3组病灶大小、体积及实性成分的对比差异有统计学意义(F=5.2462、4.1562、4.1708,P值均V0.05);IAC、MIA、浸润前病变3组肺磨玻璃结节CT征象分叶征、毛刺征、胸膜凹陷征的对比差异有统计学意义(F=6.1578、4.2587、7.1524,P值均V0.05);根据浸润程度分为浸润组(IAC)与无或微浸润组(MIA和浸润前病变),病灶大小、病灶体积、病灶实性成分差异有统计学意义(t=7.5770、8.7685、6.6039,P值均<0.05),分叶征、毛刺征、空泡征、胸膜凹陷征的占比差异有统计学意义(Х^2=54.7406、31.2348、4.8469、56.0996,P值均<0.05)。结论肺磨玻璃结节的大小、体积、实性成分及CT征象比例可为不同病理类型的鉴别诊断提供准确信息,通过明确诊断进行有效的对应治疗,亦可促使肺癌患者生存率提升。
Objective To explore the value of CT in the diagnosis of pulmonary ground glass nodules.Methods A total of 256 patients with ground-glass CT findings from June 2015 to June 2019 were enrolled in the First Hospital of Shijiazhuang.The imaging data of 241 patients with pulmonary ground glass nodules were analyzed,and 134 cases were compared.Invasive adenocarcinoma(IAC),76 cases of microinvasive adenocarcinoma(MIA),31 lesions in patients with pre-invasive lesions,size,volume,solid components and CT signs.Results There were significant differences in the size,volume and solid components between the IAC,MIA and preinvasive lesions(F=5.246 2,4.156 2,4.170 8,all P<0.05).There were statistically significant differences in the CT signs of lobes,burrs,and pleural indentations between the IAC,MIA,and preinvasive lesions(F=6.157 8,4.258 7,7.152 4,all P<0.05);According to the degree of infiltration,it was divided into infiltration group(IAC)and no or micro infiltration group(MIA and pre-invasive lesions).There were significant differences in lesion size,lesion volume and solid components(t=7.577 0,8.768 5,6.603 9,P<0.05),there was a significant difference in the proportion of lobulated sign,burr sign,vacuole sign,and pleural indentation(Х^2=54.740 6,31.234 8,4.846 9,56.099 6,all P<0.05).Conclusions The size,volume,solid components and CT signs of lung-grinding glass nodules can provide accurate information for the differential diagnosis of different pathological types,through clear diagnosis and effective corresponding treatment,lung cancer patients can also promote the survival rate.
作者
左晓玲
左玉强
孟庆春
Zuo Xiaoling;Zuo Yuqiang;Meng Qingchun(Department of Imaging Center,the First Hospital of Shijiazhuang Central Court yard,Shijiazhuang 050011,China)
出处
《国际呼吸杂志》
2019年第16期1254-1258,共5页
International Journal of Respiration
基金
河北省医学科学研究重点课题(20160804).
关键词
肺磨玻璃结节
CT
临床诊断
Pulmonary ground glass nodules
CT
Clinical diagnosis
作者简介
通信作者:左晓玲,Email:wufeitao111@163.com.
